===== Emeritus Professor (M.R.) Jisnuson Svasti =====

{{:staff:jisnuson:jisanuson1.jpg|}}\\

**Born**: 25 September 1947; Bangkok, Thailand.\\

**Office address**: Laboratory of Biochemistry, Chulabhorn Research Institute,\\
54 Kamphaeng Phet 6 Talat Bang Khen, Lak Si, Bangkok 10210, Thailand\\

**Tel**: +662-5538561 (office), +6681-8212135(mobile)\\

**Fax**: +662-259-6634\\

**Position**: Directory, Laboratory of Biochemistry, Chulabhorn Research Institute, and Emeritus Professor of Biochemistry, Mahidol University, Bangkok\\

**E-mail**: Jisnuson.sva@mahidol.ac.th, Jisnuson@cri.or.th, Jisnuson@gmail.com\\

**Website**: https://www.sc.mahidol.ac.th/scbc/Svasti_J\\

===== Research Interests =====
General interests in studying structure-function relationships in proteins and enzymology. Past experiences include study of Plasma Proteins, Proteins unique to the male reproductive system, Abnormal hemoglobins. Current research interests include: Inborn errors of metabolism; Protein changes in cancer, anti-cancer agents from natural products; Glycosidase enzymes and glycosides; Protein changes caused by environmental contamination.\\

===== Education =====
  * Educated in England (1954-1972)
  * Cheam School, Headley, Nr. Newbury, Berkshire, 1957-1960
  * Rugby School, Rugby, Warwickshire, 1960-1965
  * Trinity College, Cambridge University, 1965-1972

===== Degrees =====
  * B.A.(Hons) Natural Sciences (Biochemistry), University of Cambridge, U.K., 1968
  * M.A., Natural Sciences, University of Cambridge, U.K. 1972
  * Ph.D., MRC Laboratory of Molecular Biology, University of Cambridge, U.K. Thesis title: Sequence Studies on Mouse Immunoglobulins Supervisor: Dr..Cesar Milstein, F.R.S. (Nobel laureate), 1972
  * D.Sc. (Honoris causa), Biochemistry, Mahidol University, Thailand, 2013
  * D.Sc. (Honoris causa), Biochemistry, Suranaree University of Technology, Thailand, 2015

===== Academic Positions =====

  * Lecturer (1972-1975), Assistant Professor (1975-1978), Associate Professor (1979-1982), Professor (1982-2002), Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand
  * Senior Research Associate, Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, Texas 77550, U.S.A., 1976-1977
  * Chairman, Department of Biochemistry, Faculty of Science, Mahidol University, 1980-84
  * Vice-President for International Relations, Mahidol University, 1997-1999
  * Head, Center for Protein Structure & Function, Mahidol University, Bangkok, 2001-2012
  * Dean, Faculty of Graduate Studies, Mahidol University, 2005-2007
  * Chair, International Relations Policy Committee, Mahidol University, 2007-10, 2015-18
  * Director, Laboratory of Biochemistry, Chulabhorn Research Institute, since 1987
  * Faculty Member, Applied Biological Sciences Program, Chulabhorn Graduate Institute, 2015-

===== International Activities =====

  * Coordinating Committee, Asian Network of Biological Science (ANBS), 1979-1981
  * Treasurer, Federation of Asian and Oceanian Biochemists (FAOB), 1980-1986
  * President, Federation of Asian and Oceanian Biochemists (FAOB), 1990-1992
  * Member, Committee on Symposia (1996-2002) and Thai Delegate (1996-2009), International Union of Biochemistry and Molecular Biology (IUBMB)
  * Editorial Board, Molecules & Cells, Korea, since 2003
  * Governing Council, Asia-Pacific International Molecular Biology Network (IMBN), since 1998
  * Council Member, Asian & Oceanic Human Proteome Organization (AOHUPO), 2004-16
  * Management Board, Science Council of Asia (SCA), 2008-2011
  * Treasurer, Federation of Asian Scientific Academies & Societies (FASAS), 2008-2012
  * Steering Committee, Asian-Pacific Protein Association (APPA), 2010-2016
  * Member, Evaluation Committee, TWAS Biology Prize, 2011-2015
  * International Committee, Asian Science Camp, since 2015
  * International Advisory Committee, Synchrotron Light Research Institute, Thailand, 2016-19
  * President, Asia Pacific Protein Association (APPA), 2017-2018

===== Local Activities =====

  * Chairman, Prajadhipok-Rambhai Barni Foundation (since 2017) and Deputy Chairman Memorial Foundation for H.M. King Rama VII-Queen Rambhai Barni (since 2012)
  * Deputy Chairman, Cambridge-Thai Foundation (since 2013)
  * Chairman (1986-87) & Advisor (since 1988), Biochemistry and Molecular Biology Section, Science Society of Thailand
  * Editor-in-Chief, ScienceAsia, Journal of the Science Society of Thailand, 2001-2007
  * Honorary Jury, UNESCO-L’Oreal Women in Science Program, Thailand, since 2002
  * Committee, National Research Council of Thailand (Chemistry & Pharmacy), 2002-2016
  * Council Member, Mahidol University (2005-2007), Huachiew Chalermphrakiet University (2004-2015), Christian University of Thailand (2009-2016) and Siam University (since 2014)
  * Co-founder and President, Protein Society of Thailand, since 2004
  * President, Science Society of Thailand under the Patronage of H.M. the King, 2008-2011
  * Board of Directors, National Science Museum, Thailand, 2008-2011
  * Board of Directors, Synchrotron Light Research Institute, Thailand, 2008-2013
  * Committee, Promotion of Academic Olympiads & Development of Science Education Foundation, since 2008
  * Committee Member, Council for the Science and Technology Profession, 2009-2012
  * Co-founder and Chairman, Marsi Foundation. since 2009
  * Chairman, Education Committee, Thai Toray Science Foundation, since 2012

===== Professional Societies =====

  * Life Member, Science Society of Thailand, since 1972; Physics Society of Thailand, since 1986; Chemical Society of Thailand, since 1991; Thai Biotechnology Society since 1992; Protein Society of Thailand, since 2006
  * Member, Biochemical Society, U.K., 1981-2008; Member, Protein Society, U.S.A., 1997-present; Member, Society for Glycobiology, U.S.A., 2001-present

===== International Awards & Honours =====

  * Honorary Member, Federation of Asian and Oceanian Biochemists and Molecular Biologists, 1994
  * Honorary Member, Philippine Society of Biochemistry and Molecular Biology, 1995
  * Elected Fellow, Academy of Sciences for the Developing World (TWAS), 1996
  * A-IMBN Distinguished Lecture Award, Asia-Pacific International Molecular Biology Network, 2011

===== Local Awards & Honours =====

  * Mahidol University Prize for Excellence in Research 1982
  * Outstanding Researcher Award, Ministry of University Affairs, 1998
  * Senior Research Fellow, Thailand Research Fund, 2001-2006
  * Outstanding Scientist of Thailand Award, Foundation for Promotion of Science & Technology, 2002
  * Outstanding Researcher, Chemistry & Pharmacy, National Research Council of Thailand, 2003
  * Outstanding Lecturer, Council of the University Faculty Senates of Thailand, 2005
  * 40th Sood Sangvichien Lectureship and Gold Medal Award, 2009

===== Royal Decorations =====

  * Knight Grand Cordon (special class), Most Noble Order of the Crown of Thailand, 1993
  * Knight Grand Cordon (special class) the Most Exalted Order of the White Elephant, 1998
  * Dushdi Mala Medal, 2005

===== Publications =====

  * Publications information available on ORCID: https://orcid.org/0000-0002-2217-4517
  * 218 Articles (201 research & 17 education/academic articles) in international journals listed in Scopus and ISI-WOS; 3,201 citations, H-index = 32 (Scopus); 4,549 citations, H-index=41 (Google Scholar)
  * 10 Other Articles at International Level & 33 Articles in Proceedings of International Conferences
  * 3 Textbooks in Thai & 1 Manual

===== Selected Publications =====

==== A. Research Articles in International Journals ====

  - Svasti, J. and Milstein, C. (1970) Variability of Interchain Binding of Immunoglobulins: interchain bridges of mouse IgG1. Nature (Lond.) 228: 933-935.
  - Svasti, J. and Milstein, C. (1972) The Disulphide Bridges of a Mouse Immunoglobulin G1 Protein. Biochem. J. 126: 837-850.
  - Svasti, J. and Milstein, C. (1972) The Complete Amino Acid Sequence of a Mouse Kappa Light Chain. Biochem. J. 128: 427-444.
  - Svasti, J. and Milstein, C. (1972) The Parallel Nature of the Interchain Disulphide Bonds of Immunoglobulins: studies on a mouse IgG1 myeloma protein. Europ. J. Biochem. 31: 405-422.
  - Adetugbo, K., Poskus, E., Svasti, J., and Milstein, C. (1975) Mouse Immunoglobulin Subclasses: cyanogen bromide fragments and partial sequence of a gamma 1 chain. Europ. J. Biochem. 56: 503-519.
  - Svasti, M.R. J. and Viriyachai, S. (1975) The Purification of Lactate Dehydrogenase Isozymes LDH-A4, LDH-B4 and LDH-C4 from Human Tissues. J. Sci. Soc. Thailand 1: 57-71.
  - Pongsawasdi, P. and Svasti, J. (1976) The Heterogeneity of the Protamines from Human Spermatozoa. Biochim. Biophys. Acta 434: 462- 473.
  - Svasti, M.R. J., Prawatmuang, P., Vajanamarhutue, C., Kadjaphai, A., Wangthammang, S. and Talupphet, N. (1976) The Presence of Two IgG Subclasses in Waterbuffalo Immunoglobulins. J. Sci. Soc. Thailand 2: 56-66.
  - Svasti, J. (1977) An Addition at the C-terminus of Water-Buffalo Immunoglobulin Lambda Chains. Biochem. J. 161: 185-187.
  - Svasti, J. and Bowman, B.H. (1978) Human Group-Specific Component: changes in electrophoretic mobility resulting from vitamin D-binding and from neuraminidase digestion. J. Biol. Chem. 252: 4188-4194.
  - Svasti, J. and Talupphet, N. (1979) Improvement in the Resolution of Human Sperm Protamines by Use of Iodoacetamide as Labelling Agent. Biochim. Biophys. Acta 577: 221-225.
  - Svasti, J., Kurosky, A., Bennett, A. and Bowman, B.H. (1979) Molecular Basis for the Three Major Forms of Human Serum Vitamin D Binding Protein (Group-Specific Component). Biochemistry 18: 1161- 1167.
  - Toowicharanont P. and Svasti, J. (1980) A Logical Approach to the Isolation of Lactate Dehydrogenase Isozyme X from Human Testes: a general rationale for the isolation of homotetrameric LDH isozymes. Experientia 36: 37-38.
  - Surarit, R. and Svasti, J. (1980) Effect of Ligand Binding on the Conformation of Human Plasma Vitamin D Binding Protein (Group-Specific Component). Biochem. J. 191:404-410.
  - Surinrat, P., Svasti, J. and Surarit, R. (1981) Improved Purification and Fluorescence Changes upon Activation of Human Seminal Plasma Acidic Protease. Biochim. Biophys. Acta 659: 38-47.
  - Anguravirutt, S. and Svasti, J. (1981) A New Procedure for the Purification of Rat Testis-Specific Histone TH2B Involving Affinity Related Chromatography. Arch. Biochem. Biophys. 210: 412-416.
  - Wattanaseree, J. and Svasti, J. (1983) Human Testis-Specific Histone TH2B: Fractionation and Peptide Mapping. Arch. Biochem. Biophys. 225: 892-897.
  - Wattanaseree, J., Svasti, J., Bubpaniroj, P. and Mitranond, V. (1984) Effect of Vitamin A Deficiency on the Testis-Specific Basic Proteins of the Rat. J. Biochem. (Tokyo) 95: 179-186.
  - Reid, W.A., Vongsorasak, L., Svasti, J., Valler, M.J. and Kay, J. (1984) Identification of the Acid Proteinase in Human Seminal Fluid as a Gastricsin Originating in the Prostate. Cell Tiss. Res. 236: 597- 600.
  - Yongvanich, T. and Svasti, J. (1984) Structural Differences between Somatic H2B and Testis- Specific TH2B Histones of the Rat. Experientia 40: 845-846.