====== Laboratory of Medicinal Chemistry ====== [[/lab/medicinal_chemistry|Home]] | [[/lab/medicinal_chemistry/res_act|Research]] | [[/lab/medicinal_chemistry/acad_act|Academic]] | **Publications** | [[/lab/medicinal_chemistry/staff|Staffs]] | [[/lab/medicinal_chemistry/contact|Contact]] ==== Recent Publications (2008 - present) ==== - Tangdenpaisal K, Ruchirawat S, Ploypradith P. Synthesis of the Thyroid Hormone Analog GC-1 //via// Bi(OTf)3-Catalyzed Benzylation. Tetrahedron **2014**; //70//: in press. [[http://www.sciencedirect.com/science/article/pii/S0040402014010771|Abstract]] - Tummatorn J, Krajangsri S, Norseeda K, Thongsornkleeb C, Ruchirawat S. A New Synthetic Approach to 6-Unsubstituted Phenanthridine and Phenanthridine-like Compounds under Mild and Metal-free Conditions. Org. Biomol. Chem. **2014**; //12//: 5077-5081. [[http://www.ncbi.nlm.nih.gov/pubmed/24914621|Abstract]] - Tummatorn J, Gleeson MP, Krajangsri S, Thongsornkleeb C, Ruchirawat S. ZrCl4-Promoted Facile Synthesis of Indole Derivatives. RSC Adv. **2014**; //4//: 20048–20052. [[http://pubs.rsc.org/en/content/articlelanding/2014/ra/c4ra02158d#!divAbstract|Abstract]] - Worayuthakarn R, Boonya-udtayan S, Ruchirawat S, Thasana N. Total Synthesis of Unsymmetrical Benzils, Scandione and Calophione A. Eur. J. Org. Chem. **2014**; //(12)//: 2496-2507. [[http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201301722/abstract|Abstract]] - Nealmongkol P, Tangdenpaisal K, Ruchirawat S, Thasana N. Cu(I)-mediated Lactone Formation in Subcritical Water: A Benign Synthesis of Benzopyranones and Urolithins A-C. Tetrahedron **2013**; //69//: 9277-9283. [[http://www.sciencedirect.com/science/article/pii/S004040201301332X|Abstract]] - Sarnpitak P, Trongchit K, Kostenko Y, Sathalalai S, Gleeson MP, Ruchirawat S, Ploypradith P. Synthesis of Substituted 2-Arylindanes from E-(2-Stilbenyl)methanols //via// Lewis acid-mediated Cyclization and Nucleophililc Transfer from Trialkylsilyl Reagents. J. Org. Chem. **2013**; //78//: 8281-8296. [[http://www.ncbi.nlm.nih.gov/pubmed/23889061|Abstract]] - Tummatorn J, Thongsornkleeb C, Ruchirawat S, Gettongsong T. Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Ethyl Esters from Arylmethyl Azides //via// a Domino Process. Org. Biomol. Chem. **2013**; //11//: 1463-1467. [[http://www.ncbi.nlm.nih.gov/pubmed/23361444|Abstract]] - Tangdenpaisal K, Phakhodee W, Ruchirawat S, Ploypradith P. Facile Synthesis of Diarylmethanes //via// Quinone Methides. Tetrahedron **2013**; //69//: 933-941. [[http://www.sciencedirect.com/science/article/pii/S0040402012016833|Abstract]] - Boonya-Udtayan S, Eno M, Ruchirawat S, Mahidol C, Thasana N. Palladium-Catalyzed Intramolecular C-H Amidation: Synthesis and Biological Activities of Indolobenzazocin-8-ones. Tetrahedron **2012**; //68//: 10293-10301. [[http://www.sciencedirect.com/science/article/pii/S0040402012015475|Abstract]] - Tummatorn J, Thongsornkleeb C, Ruchirawat S. Acid-Promoted Rearrangement of Arylmethyl Azides: Applications toward the Synthesis of //N//-Arylmethyl Arenes and Polycyclic Heteroaromatic Compounds. Tetrahedron **2012**; //68//: 4732-4739. [[http://www.sciencedirect.com/science/article/pii/S0040402012005224|Abstract]] - Worayuthakarn R, Nealmongkol P, Ruchirawat S, Thasana N. Synthesis of Benzoindoloquinolizines //via// a Cu(I)-mediated C-N Bond Formation. Tetrahedron **2012**; //68//: 2864-2875. [[http://www.sciencedirect.com/science/article/pii/S0040402012001603|Abstract]] - Wittayalai S, Sathalalai S, Thorroad S, Worawittayanon P, Ruchirawat S, Thasana N. Lycophlegmariols A-D: Cytotoxic Serratene Triterpenoids from the Club Moss //Lycopodium phlegmaria// L. Phytochemistry **2012**; //76//: 117-123. [[http://www.ncbi.nlm.nih.gov/pubmed/22281380|Abstract]] - Disadee W, Ploypradith P, Aree T, Chaichit N, Ruchirawat S. A Novel Approach for the Synthesis of Lophocladines A, B and C1 Analogues. Tetrahedron Lett. **2011**; //52//: 6142-6144. [[http://www.sciencedirect.com/science/article/pii/S004040391101553X|Abstract]] - Radomkit S, Sarnpitak P, Tummatorn J, Batsomboon P, Ruchirawat S, Ploypradith P. Pt(IV)-catalyzed Generation and [4+2]-Cycloaddition Reactions of //O//-Quinone Methides. Tetrahedron **2011**; //67//: 3904-3914. [[http://www.sciencedirect.com/science/article/pii/S0040402011004121|Abstract]] - Gleeson MP, Deechongkit S, Ruchirawat S. Molecular Dynamics Investigation of Psalmopeotoxin I. Probing the Relationship between 3D Structure, Anti-malarial Activity and Thermal Stability. J. Mol. Model. **2011**; //17//: 769-775. [[http://www.ncbi.nlm.nih.gov/pubmed/20544240|Abstract]] - Boonya-Udtayan S, Yotapan N, Woo C, Bruns CJ, Ruchirawat S, Thasana N. Synthesis and Biological Activities of Azalamellarins. Chem. Asian J. **2010**; //5//: 2113-2123. [[http://www.ncbi.nlm.nih.gov/pubmed/20677319|Abstract]] - Chittchang M, Gleeson MP, Ploypradith P, Ruchirawat S. Assessing the Drug-likeness of Lamellarins, a Marine-derived Natural Product Class with Diverse Oncological Activities. Eur. J. Med. Chem. **2010**; //45//: 2165-2172. [[http://www.ncbi.nlm.nih.gov/pubmed/20167395|Abstract]] - Kamolkijkarn P, Prasertdee T, Netirojjanakul C, Sarnpitak P, Ruchirawat S, Deechongkit S. Synthesis, Biophysical, and Biological Studies of Wild-Type and Mutant Psalmopeotoxins-anti-malarial Cysteine Knot Peptides from //Psalmopoeus cambridgei//. Peptides **2010**; //31//: 533-540. [[http://www.ncbi.nlm.nih.gov/pubmed/20067814|Abstract]] - Tummatorn J, Ruchirawat S, Ploypradith P. A Convergent General Strategy for the Functionalized 2-Aryl Cycloalkylfused Chromans: Intramolecular Hetero-Diels-Alder Reactions of //ortho//-Quinone Methides. Chem. Eur. J. **2010**; //16//: 1445-1448. [[http://www.ncbi.nlm.nih.gov/pubmed/20039342|Abstract]] - Tangdenpaisal K, Sualek S, Ruchirawat S, Ploypradith P. Factors Affecting Orthogonality in the Deprotection of 2,4-Di-protected Aromatic Ethers Employing Solid-supported Acids. Tetrahedron **2009**; //65//: 4316-4325. [[http://www.sciencedirect.com/science/article/pii/S0040402009004852|Abstract]] - Batsomboon P, Phakhodee W, Ruchirawat S, Ploypradith P. Generation of //ortho//-Quinone Methides by p-TsOH on Silica and Their Hetero-Diels-Alder Reactions with Styrenes. J. Org. Chem. **2009**; //74//: 4009-4012. [[http://www.ncbi.nlm.nih.gov/pubmed/19385608|Abstract]] - Chittchang M, Batsomboon P, Ruchirawat S, Ploypradith P. Cytotoxicities and Structure-activity Relationships of Natural and Unnatural Lamellarins toward Cancer Cell Lines. ChemMedChem **2009**; //4//: 457-465. [[http://www.ncbi.nlm.nih.gov/pubmed/19152364|Abstract]] - Phakhodee W, Ploypradith P, Sahakitpichan P, Ruchirawat S. A New Synthetic Approach towards Isoquinobenzazepinone and Isoindolinobenzazepinone using Acid-mediated Cyclisation and Heck Reaction. Tetrahedron **2009**; //65//: 351-356. [[http://www.sciencedirect.com/science/article/pii/S0040402008018346|Abstract]] - Worayuthakarn R, Boonya-udtayan S, Arom-oon E, Ploypradith P, Ruchirawat S, Thasana N. Synthesis of Unsymmetrical Benzil Licoagrodione. J. Org. Chem. **2008**; //73//: 7432-7435. [[http://www.ncbi.nlm.nih.gov/pubmed/18712927|Abstract]] - Phakhodee W, Sahakitpichan P, Deechongkit S, Ruchirawat S. Investigation of the Acid-mediated Cyclisation of Amide Acetal for the Synthesis of Benzazepinone. Heterocycles **2008**; //75//: 1963-1970. [[http://www.heterocycles.jp/newlibrary/libraries/abst/02779|Abstract]] - Thasana N, Bjerke-Kroll B, Ruchirawat S. A Facile Synthesis of Telisatin A //via// Microwave-promoted Annulation and Reformatsky Reaction. Synlett **2008**; 505-508. [[https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2008-1042764|Abstract]] ==== Publications from Collaborations ==== - Maibunkaew T, Thongsornkleeb C, Tummatorn J, Bunrit A, Ruchirawat S. Practical and Metal-free Electrophilic Aromatic Halogenation by Inter­halogen Compounds Generated //in situ// from //N//-Halosuccinimide and Catalytic TMSCl. Synlett **2014**; //25//: 1769-1775. [[https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0034-1378225|Abstract]] - Sahakitpichan P, Mahidol C, Disadee W, Chimnoi N, Ruchirawat S, Kanchanapoom T. Glucopyranosyloxybenzyl Derivatives of (//R//)-2-Benzylmalic Acid and (//R//)-Eucomic Acid, and an Aromatic Glucoside from the Pseudobulbs of //Grammatophyllum speciosum//. Tetrahedron **2013**; //69//: 1031-1037. [[http://www.sciencedirect.com/science/article/pii/S0040402012018005|Abstract]] - Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis and Cytotoxicity of Novel //N//-Sulfonyl-1,2,3,4-tetrahydroisoquinoline Thiosemicarbazone Derivatives. Med. Chem. Res. **2013**; //22//: 267-277. [[http://link.springer.com/article/10.1007%2Fs00044-012-0025-y?LI=true#page-1|Abstract]] - Phakeovilay C, Disadee W, Sahakitpichan P, Sitthimonchai S, Kittakoop P, Ruchirawat S, Kanchanapoom T. Phenylethanoid and Flavone Glycosides from //Ruellia tuberosa// L. J. Nat. Med. **2013**; //67//: 228-233. [[http://www.ncbi.nlm.nih.gov/pubmed/22447282|Abstract]] - Boonyarattanakalin S, Ruchirawat S, Gleeson MP. Ring Opening Polymerization of Mannosyl Tricyclic Orthoesters: Rationalising The Stereo and Regioselectivity of Glycosidic Bond Formation using Quantum Chemical Calculations. Med. Chem. Commun. **2013**; //4//: 265-268. [[http://pubs.rsc.org/en/content/articlelanding/2013/MD/C2MD20178J|Abstract]] - Pingaew R, Tongraung P, Worachartcheewan A, Nantasenamat C, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Cytotoxicity and QSAR Study of (Thio)ureas Derived from Phenylalkylamines and Pyridylalkylamines. Med. Chem. Res. **2012**: DOI 10.1007/s00044-012-0402-6. [[http://link.springer.com/article/10.1007/s00044-012-0402-6#page-1|Abstract]] - Thongsornkleeb C, Rabten W, Bunrit A, Tummatorn J, Ruchirawat S. Facile Access to 2,5-Disubstituted-4-chloromethyl-3-iodofuran Derivatives via ICl-Mediated Cyclization of 1-Alkyl-2-alkynylallylic Alcohols. Tetrahedron Lett. **2012**; //53//: 6615-6619. [[http://www.sciencedirect.com/science/article/pii/S0040403912017248|Abstract]] - Prachayasittikul S, Pingaew R, Yamkamon U, Worachartcheewan A, Wanwimolruk S, Ruchirawat S, Prachayasittikul V. Chemical Constituents and Antioxidant Activity of //Hydnophytum formicarum// Jack. Int. J. Pharmacol. **2012**; //8//: 440-444. [[http://scialert.net/abstract/?doi=ijp.2012.440.444|Abstract]] - Siripong P, Yahuafai J, Piyaviriyakul S, Kanokmedhakul K, Koide H, Ishii T, Shimizu K, Ruchirawat S, Oku N. Inhibitory Effect of Liposomal Rhinacanthin-N Isolated from //Rhinacanthus nasutus// on Pulmonary Metastasis in Mice. Biol. Pharm. Bull. **2012**; //35//: 1197-1200. [[http://www.ncbi.nlm.nih.gov/pubmed/22791173|Abstract]] - Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis and Cytotoxicity of Novel 2,2'-Bis- and 2,2',2''-Tris-indolyl-methanes-based Bengacarboline Analogs. Arch. Pharm. Res. **2012**; //35//: 949-954. [[http://www.ncbi.nlm.nih.gov/pubmed/22870803|Abstract]] - Prachayasittikul S, Worachartcheewan A, Pingaew R, Suksrichavalit T, Isarankura-Na-Ayudhya C, Ruchirawat S, Prachayasittikul V. Metal Complexes of Uracil Derivatives with Cytotoxicity and Superoxide Scavenging Activity. Lett. Drug Des. Discov. **2012**; //9//: 282-287. [[http://www.ingentaconnect.com/content/ben/lddd/2012/00000009/00000003/010aj|Abstract]] - Worawittayanon P, Ruadreo J, Disadee W, Sahakitpichan P, Sitthimonchai S, Thasana N, Ruchirawat S, Kanchanapoom T. Iridoid and Flavone Glycosides from //Asystasia gangetica// subsp. micrantha and //Asystasia salicifolia// and Their Antioxidant Activities. Biochem. Syst. Ecol. **2012**; //40//: 38-42. [[http://www.sciencedirect.com/science/article/pii/S0305197811001785|Abstract]] - Disadee W, Mahidol C, Sahakitpichan P, Sitthimonchai S, Ruchirawat S, Kanchanapoom T. Unprecedented Furan-2-carbonyl C-Glycosides and Phenolic Diglycosides from //Scleropyrum pentandrum//. Phytochemistry **2012**; //74//: 115-122. [[http://www.ncbi.nlm.nih.gov/pubmed/22152976|Abstract]] - Prachayasittikul S, Worachartcheewan A, Yainoy S, Lomchoey N, Kittiphatcharin P, Ruchirawat S, Prachayasittikul V. Antioxidant and Antimicrobial Activities of //Saraca thaipingensis// Cantley ex Prain. Asian Pac. J. Trop. Biomed. **2012**; //2//: S796-S799. [[http://www.apjtb.com/zz/2012s2/61.pdf|Abstract]] - Adachi M, Higuchi K, Thasana N, Yamada H, Nishikawa T. Stereocontrolled Synthesis of an Indole Moiety of Sespendole and Stereochemical Assignment of the Side Chain. Org. Lett. **2012**, //14//, 114-117. [[http://www.ncbi.nlm.nih.gov/pubmed/22126279|Abstract]] - Doungsoongnuen S, Worachartcheewan A, Pingaew R, Suksrichavalit T, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Investigation on Biological Activities of Anthranilic Acid Sulfonamide Analogs. EXCLI J. **2011**; //10//: 155-161. [[http://www.excli.de/vol10/Prachayasittikul10_2011/Prachayasittikul_071011_proof.pdf|Abstract]] - Sripha K, Zlotos DP, Holzgrabe U, Ruchirawat S. A New Synthetic Approach to Pentacyclic Ring, 6,7,14,15-Tetrahydro[1,5]Diazocino[1,2-//a//:6,5-//a//']-8-Dihydrodiindole. Heterocycles **2011**; //83//: 2627-2633. [[http://www.heterocycles.jp/newlibrary/payments/form/22152/fulltext|Abstract]] - Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. 3-Hydroxydihydrobenzofuran Glucosides from //Gnaphalium polycaulon//. Chem. Pharm. Bull. **2011**; //59//: 1160-1162. [[http://www.ncbi.nlm.nih.gov/pubmed/21881262|Abstract]] - Hutacharoen P, Ruchirawat S, Boonyarattanakalin S. Biological Activities of Synthetic Oligosaccharides and Glycolipids from Mycobacteria. J. Carbohydr. Chem. **2011**; //30//: 415-437. [[http://www.tandfonline.com/doi/full/10.1080/07328303.2011.621041#.UhbcrhD4UyY|Abstract]] - Treeratanapiboon L, Worachartcheewan A, Suksrichavalit T, Kiatfuengfoo R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Bioactive 4-Hydroxycinnamide and Bioactivities of //Polyalthia cerasoides//. EXCLI J. **2011**; //10//: 16-22. [[http://www.excli.de/vol10/prachayasittikul03_2011/prachayasittikul_09032011_proof.pdf|Abstract]] - Pailee P, Prachyawarakorn V, Mahidol C, Ruchirawat S, Kittakoop P. Protoberberine Alkaloids and Cancer Chemopreventive Properties of Compounds from //Alangium salviifolium//. Eur. J. Org. Chem. **2011**, (20-21): 3809-3814. [[http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100423/abstract|Abstract]] - Bunrit A, Ruchirawat S, Thongsornkleeb C. A Simple Microwave-assisted Preparation of 2-Bromo-1-alkenes from 1-Alkynes using the LiBr-TMSCl-TEAB Reagent System. Tetrahedron Lett. **2011**; //52//: 3124-3127. [[http://www.sciencedirect.com/science/article/pii/S0040403911005983|Abstract]] - Disadee W, Mahidol C, Sahakitpichan P, Sitthimonchai S, Ruchirawat S, Kanchanapoom T. Flavonol 3-//O//-Robinobiosides and 3-//O//-(2″-//O//-α-Rhamnopyranosyl)-robinobiosides from //Sesuvium portulacastrum//. Tetrahedron **2011**; //67//: 4221-4226. [[http://www.sciencedirect.com/science/article/pii/S0040402011005485|Abstract]] - Sahakitpichan P, Mahidol C, Disadee W, Ruchirawat S, Kanchanapoom T. Unusual Glycosides of Pyrrole Alkaloid and 4′-Hydroxyphenylethanamide from Leaves of //Moringa oleifera//. Phytochemistry **2011**; //72//: 791-795. [[http://www.ncbi.nlm.nih.gov/pubmed/21439596|Abstract]] - Panseeta P, Lomchoey K, Prabpai S, Kongsaeree P, Suksamrarn A, Ruchirawat S, Suksamrarn S. Antiplasmodial and Antimycobacterial Cyclopeptide Alkaloids from the Root of //Ziziphus mauritiana//. Phytochemistry **2011**; //72//: 909-915. [[http://www.ncbi.nlm.nih.gov/pubmed/21450320|Abstract]] - Kanintronkul Y, Worayuthakarn R, Thasana N, Winayanuwattikun P, Pattanapanyasat K, Surarit R, Ruchirawat S, Svasti J. Overcoming Multidrug Resistance in Human Lung Cancer with Novel Benzo[//a//]quinolizin-4-ones. Anticancer Res. **2011**; //31//: 921-927. [[http://www.ncbi.nlm.nih.gov/pubmed/21498714|Abstract]] - Prachayasittikul S, Worachartcheewan A, Nantasenamat C, Chinworrungsee M, Sornsongkhram N, Ruchirawat S, Prachayasittikul V. Synthesis and Structure-activity Relationship of 2-Thiopyrimidine-4-one Analogs as Antimicrobial and Anticancer Agents. Eur. J. Med. Chem. **2011**; //46//: 738-742. [[http://www.ncbi.nlm.nih.gov/pubmed/21216051|Abstract]] - Thipnate P, Chittchang M, Thasana N, Saparpakorn P, Ploypradith P, Hannongbua S. Exploring the Molecular Basis for Selective Cytotoxicity of Lamellarins against Human Hormone-dependent T47D and Hormone-independent MDA-MB-231 Breast Cancer Cells. Monatsh. Chem. **2011**; //142//: 97-109. [[http://link.springer.com/article/10.1007/s00706-010-0409-y|Abstract]] - Pungkham H, Swatdipakdi N, Theerasilp M, Chittchang M, Karnkla S, Ploypradith P, Nasongkla N. PEG-b-PCL and PEG-b-PLA Polymeric Micelles as Nanocarriers for Lamellarin N Delivery. Conf. Proc. IEEE Eng. Med. Biol. Soc. **2011**, 3245-3248. [[http://www.ncbi.nlm.nih.gov/pubmed/22255031|Abstract]] - Prachayasittikul S, Pingaew R, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. A New Sulfoxide Analog of 1,2,3,6-Tetrahydrophenylpyridine and Antimicrobial Activity. EXCLI J. **2010**; //9//: 102-107. [[http://www.excli.de/vol9/Prachayasittikul09_2010/Prachayasittikul_270910_proof.pdf|Abstract]] - Noiarsa P, Ruchirawat S, Kanchanapoom T. Acanmontanoside, a New Phenylethanoid Diglycoside from //Acanthus montanus//. Molecules **2010**; //15//: 8967-8972. [[http://www.ncbi.nlm.nih.gov/pubmed/21139534|Abstract]] - Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. L-(-)-(//N//-//trans//-Cinnamoyl)-arginine, an Acylamino Acid from //Glinus oppositifolius// (L.) Aug. DC. Molecules **2010**; //15//: 6186-6192. [[http://www.ncbi.nlm.nih.gov/pubmed/20877215|Abstract]] - Prachayasittikul S, Wongsawatkul O, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Vasorelaxation and Superoxide Scavenging Activities of Orotic Acid. Int. J. Pharmacol. **2010**; //6//: 413-418. [[http://scialert.net/fulltext/?doi=ijp.2010.413.418&org=11|Abstract]] - Prachayasittikul S, Wongsawatkul O, Suksrichavalit T, Ruchirawat S, Prachayasittikul V. Bioactivity Evaluation of //Eclipta prostrate// Linn: a Potential Vasorelaxant. Eur. J. Sci. Res. **2010**; //44//: 167-176. [[http://www.eurojournals.com/ejsr_44_2_01.pdf|Abstract]] - Lirdprapamongkol K, Sakurai H, Suzuki S, Koizumi K, Prangsaengtong O, Viriyaroj A, Ruchirawat S, Svasti J, Saiki I. Vanillin Enhances TRAIL-induced Apoptosis in Cancer Cells through Inhibition of NF-κB Activation. In Vivo **2010**; //24//: 501-506. [[http://www.ncbi.nlm.nih.gov/pubmed/20668316|Abstract]] - Thasana N, Prapagdee B, Rangkadilok N, Sallabhan R, Aye SL, Ruchirawat S, Loprasert S. //Bacillus subtilis// SSE4 produces subtulene A, A New Lipopeptide Antibiotic Possessing an Unusual C15 Unsaturated β-Amino Acid. FEBS Lett. **2010**; //584//: 3209-3214. [[http://www.ncbi.nlm.nih.gov/pubmed/20541548|Abstract]] - Yongyat C, Ruchirawat S, Boonyarattanakalin S. Polymerization of Mannosyl Tricyclic Orthoesters for the Synthesis of α(1-6) Mannopyranan-the Backbone of Lipomannan. Bioorg. Med. Chem. **2010**; //18//: 3726-3734. [[http://www.ncbi.nlm.nih.gov/pubmed/20471841|Abstract]] - Chanthateyanonth R, Ruchirawat S, Srisitthiratkul C. Preparation of New Water-Soluble Chitosan Containing Hyperbranched-vinylsulfonic Acid Sodium Salt and Their Antimicrobial Activities and Chelation with Metals. J. Appl. Polym. Sci. **2010**; //116//: 2074-2082. [[http://onlinelibrary.wiley.com/doi/10.1002/app.31732/abstract|Abstract]] - Prachayasittikul S, Saraban P, Cherdtrakulkiat R, Ruchirawat S, Prachayasittikul V. New Bioactive Triterpenoids and Antimalarial Activity of //Diospyros rubra// Lec. EXCLI J. ** 2010**; //9//: 1-10. [[http://www.excli.de/vol9/prachaxasittikul_triterpenoids2010/prachayasittikul_proof.pdf|Abstract]] - Pingaew R, Prachayasittikul S, Ruchirawat S. Synthesis, Cytotoxic and Antimalarial Activities of Benzoyl Thiosemicarbazone Analogs of Isoquinoline and Related Compounds. Molecules **2010**; //15//: 988-996. [[http://www.ncbi.nlm.nih.gov/pubmed/20335957|Abstract]] - Prachayasittikul S, Wongsawatkul O, Worachartcheewan A, Nantasenamat C, Ruchirawat S, Prachayasittikul V. Elucidating the Structure-activity Relationships of the Vasorelaxation and Antioxidation Properties of Thionicotinic Acid Derivatives. Molecules **2010**; //15//: 198-214. [[http://www.ncbi.nlm.nih.gov/pubmed/20110883|Abstract]] - van Duursen MBM, Nijmeijer SM, Ruchirawat S, van den Berg M. Chemopreventive Actions by Enterolactone and 13 VIOXX®-related Lactone Derivatives in H295R Human Adrenocortical Carcinoma Cells. Toxicol. Lett. **2010**; //192//: 271-277. [[http://www.ncbi.nlm.nih.gov/pubmed/19913079|Abstract]] - Prachayasittikul S, Limnusont P, Pingaew R, Ruchirawat S, Prachayasittikul V. β-(1-Adamantylthio)pyridine Analogs as Antimicrobials and Antimalarials. EXCLI J. **2009**; //8//: 35-40. [[http://www.excli.de/vol8/prachayasittikul_02_2009/prachayasittikul_antimicrobials_proof.pdf|Abstract]] - Prachayasittikul S, Treeratanapiboon L, Ruchirawat S, Prachayasittikul V. Novel Activities of 1-Adamantylthiopyridines as Antibacterials, Antimalarials and Anticancers. EXCLI J. **2009**; //8//: 121-129. [[http://www.excli.de/vol8/prachayasittikul_06_2009/prachayasittikul_novel_activities_proof.pdf|Abstract]] - Prachayasittikul S, Buttrawong K, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Isolation of Bioactive Metabolites from Root Extracts of //Polyalthia debilis//. Eur. J. Sci. Res. **2009**; //38//: 596-603. [[http://www.eurojournals.com/ejsr_38_4_10.pdf|Abstract]] - Prachayasittikul S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V. Activities of Thiotetrahydropyridines as Antioxidant and Antimicrobial Agents. EXCLI J. **2009**; //8//: 107-114. [[http://www.excli.de/vol8/Prachayasittikul_05_2009/Prachayasittikul_thiotetrahydropyridine_proof_060509.pdf|Abstract]] - Prachayasittikul S, Manam P, Chinworrungsee M, Isarankura-Na-ayudhya C, Ruchirawat S, Prachayasittikul V. Bioactive Azafluorenone Alkaloids from //Polyalthia debilis// (Pierre) Finet & Gagnep. Molecules **2009**; //14//: 4414-4424. [[http://www.ncbi.nlm.nih.gov/pubmed/19924075|Abstract]] - Prachayasittikul S, Sornsongkhram N, Pingaew R, Techatanachai S, Ruchirawat S, Prachayasittikul V. Synthesis and Novel Bioactivities of Substituted 6-Propylthiouracils. Eur. J. Sci. Res. **2009**; //36//: 236-245. [[http://www.eurojournals.com/ejsr_36_2_06.pdf|Abstract]] - Prachayasittikul S, Sornsongkhram N, Pingaew R, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Synthesis of //N//-Substituted 5-Iodouracils as Antimicrobial and Anticancer Agents. Molecules **2009**; //14//: 2768-2779. [[http://www.ncbi.nlm.nih.gov/pubmed/19701123|Abstract]] - Siripong P, Hahnvajanawong C, Yahuafai J, Piyaviriyakul S, Kanokmedhakul K, Kongkathip N, Ruchirawat S, Oku N. Induction of Apoptosis by Rhinacanthone Isolated from //Rhinacanthus nasutus// Roots in Human Cervical Carcinoma Cells. Biol. Pharm. Bull. **2009**; //32//: 1251-1260. [[http://www.ncbi.nlm.nih.gov/pubmed/19571394|Abstract]] - Sangjun S, de Jong E, Nijmeijer S, Mutarapat T, Ruchirawat S, van den Berg M, van Duursen MB. Induction of Cell Cycle Arrest in Human MCF-7 Breast Cancer Cells by //cis//-Stilbene Derivatives Related to VIOXX®. Toxicol. Lett. **2009**; //186//: 115-122. [[http://www.ncbi.nlm.nih.gov/pubmed/19429232|Abstract]] - Khorana N, Markmee S, Ingkaninan K, Ruchirawat S, Kitbunnadaj R, Pullagurla MR. Evaluation of a New Lead for Acetylcholinesterase Inhibition. Med. Chem. Res. **2009**; //18//: 231-241. [[http://link.springer.com/article/10.1007%2Fs00044-008-9122-3#page-1|Abstract]] - Prachayasittikul S, Suphapong S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V. Bioactive Metabolites from //Spilanthes acmella// Murr. Molecules **2009**; //14//: 850-867. [[http://www.ncbi.nlm.nih.gov/pubmed/19255544|Abstract]] - Prompiboon P, Bhumiratana A, Ruchirawat S, Boucias DG, Wiwat C. Isolation of Ergosterol Peroxide from //Nomuraea rileyi// Infected Larvae of Tobacco Cutworm. World J. Microbiol. Biotechnol. **2008**; //24//: 2909-2917. [[http://link.springer.com/article/10.1007%2Fs11274-008-9830-3?LI=true#page-1|Abstract]] - Wongsawatkul O, Prachayasittikul S, Isarankura-Na-Ayudhya C, Satayavivad J, Ruchirawat S, Prachayasittikul V. Vasorelaxant and Antioxidant Activities of //Spilanthes acmella// Murr. Int. J. Mol. Sci. **2008**; //9//: 2724-2744. [[http://www.ncbi.nlm.nih.gov/pubmed/19330100|Abstract]] - Sanderson T, Renaud M, Scholten D, Nijmeijer S, van den Berg M, Cowell S, Guns E, Nelson C, Mutarapat T, Ruchirawat S. Effects of Lactone Derivatives on Aromatase (CYP19) Activity in H295R Human Adrenocortical and (Anti)androgenicity in Transfected LNCaP Human Prostate Cancer Cells. Eur. J. Pharmacol. **2008**; //593//: 92-98. [[http://www.ncbi.nlm.nih.gov/pubmed/18639541|Abstract]] - van Meeuwen JA, Nijmeijer S, Mutarapat T, Ruchirawat S, de Jong PC, Piersma AH, van den Berg M. Aromatase Inhibition by Synthetic Lactones and Flavonoids in Human Placental Microsomes and Breast Fibroblasts - a Comparative Study. Toxicol. Appl. Pharmacol. **2008**; //228//: 269-276. [[http://www.ncbi.nlm.nih.gov/pubmed/18201740|Abstract]] - Prachayasittikul S, Buraparuangsang P, Worachartcheewan A, Isarankura-Na-Ayudhya C, Ruchirawat S, Prachayasittikul V. Antimicrobial and Antioxidative Activities of Bioactive Constituents from //Hydnophytum formicarum// Jack. Molecules **2008**; //13//: 904-921. [[http://www.ncbi.nlm.nih.gov/pubmed/18463592|Abstract]] - Noiarsa P, Ruchirawat S, Otsuka H, Kanchanapoom T. Chemical Constituents from //Oldenlandia corymbosa// L. of Thai Origin. J. Nat. Med. **2008**; //62//: 249-250. [[http://www.ncbi.nlm.nih.gov/pubmed/18404335|Abstract]] - Kaewkrud W, Otsuka H, Ruchirawat S, Kanchanapoom T. Megastigmane and Flavone Glycosides from //Strophioblachia fimbricalyx// Boerl. J. Nat. Med. **2008**; //62//: 124-125. [[http://www.ncbi.nlm.nih.gov/pubmed/18404358|Abstract]] - Baunbæk D, Trinkler N, Ferandin Y, Lozach O, Ploypradith P, Ruchirawat S, Ishibashi F, Iwao M, Meijer L. Anticancer Alkaloid Lamellarins Inhibit Protein Kinases. Mar. Drugs **2008**; //6//: 514-527. [[http://www.ncbi.nlm.nih.gov/pubmed/19172192|Abstract]]