====== Laboratory of Natural Products ====== **Recent Publications (2003 - present)** -------------------------------------------------------------------------------- **2013**\\ Directed biosynthesis through biohalogenation of secondary metabolites of the marine-derived fungus //Aspergillus unguis.//[[http://pubs.rsc.org/en/content/articlelanding/2013/RA/c2ra23021f#divAbstract|Abstract]]\\ Sureram, S.; Kesornpun, C.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. RSC Adv. 2013, 3, 1781-1788. Glucopyranosyloxybenzyl derivatives of (//R//)-2-benzylmalic acid and (//R//)-eucomic acid, and an aromatic glucoside from the pseudobulbs of //Grammatophyllum speciosum//. [[http://www.sciencedirect.com/science/article/pii/S0040402012018005#divAbstract|Abstract]]\\ Sahakitpichan, P.; Mahidol, C.; Disadee, W.; Chimnoi, N.; Ruchirawat, S.; Kanchanapoom, T. Tetrahedron, 2013, 69(3),1031-1037. Phenylethanoid and Flavone Glycosides from //Ruellia tuberosa// L. [[http://link.springer.com/article/10.1007%2Fs11418-012-0658-7##divAbstract|Abstract]]\\ Phakeovilay, C.; Disadee, W.; Sahakitpichan, P.; Sitthimonchai, S.; Kittakoop, P.; Ruchirawat, S.; Kanchanapoom, T. J. Nat. Med. 2013, 67, 228-233. **2012**\\ A novel tricyclic polyketide and its biosynthetic precursor azaphilone derivatives from the endophytic fungus //Dothideomycete// sp. [[http://pubs.rsc.org/en/content/articlelanding/2012/ob/c2ob25959a#divAbstract|Abstract]]\\ Senadeera, S. P. D.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Org. Biomol. Chem., 2012, 10(35), 7220-7226. Iodo-sesquiterpene hydroquinone and brominated indole alkaloids from the Thai sponge //Smenospongia// sp. [[http://www.sciencedirect.com/science/article/pii/S0040402012009106#divAbstract|Abstract]]\\ Prawat, H.; Mahidol, C.; Kaweetripob, W.; Wittayalai, S.; Ruchirawat, S. Tetrahedron, 2012, 68(34), 6881-6886. Depsidones, aromatase inhibitors and radical scavenging agents from the marine-derived fungus //Aspergillus unguis// CRI282-03. [[https://www.thieme-connect.de/ejournals/abstract/10.1055/s-0031-1298228#divAbstract|Abstract]]\\ Sureram, S.; Wiyakrutta, S.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Planta Medica, 2012, 78(6), 582-588. Antimycobacterial activity of bisbenzylisoquinoline alkaloids from //Tiliacora triandra// against multidrug-resistant isolates of //Mycobacterium tuberculosis//. [[http://www.sciencedirect.com/science/article/pii/S0960894X12002454#divAbstract|Abstract]]\\ Sureram, S.; Senadeera, S. P. D.; Hongmanee, P.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Bioorg. Med. Chem. Lett., 2012, 22(8), 2902-2905. Nitrone formation in phosphate buffer and aqueous solutions: novel chemistry inspired by a natural product. [[http://www.sciencedirect.com/science/article/pii/S0040403912002821#divAbstract|Abstract]]\\ Pansanit, A.; Ingavat, N.; Aree, T.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Tetrahedron Lett., 2012, 53(16), 2129-2131. 5-Formylfurfuryl esters from //Duabanga grandiflora//. [[http://www.sciencedirect.com/science/article/pii/S0031942212000398#divAbstract|Abstract]]\\ Kaweetripob, W.; Mahidol, C.; Prachyawarakorn, V.; Prawat, H.; Ruchirawat, S. Phytochemistry, 2012, 76, 78-82. Unprecedented furan-2-carbonyl //C//-glycosides and phenolic diglycosides from //Scleropyrum pentandrum//. [[http://www.sciencedirect.com/science/article/pii/S0031942211004857#divAbstract|Abstract]]\\ Disadee, W.; Mahidol, C.; Sahakitpichan, P.; Sitthimonchai, S.; Ruchirawat, S.; Kanchanapoom, T. Phytochemistry, 2012, 74, 115-122. In Vitro Acanthamoebicidal Activity of Fusaric Acid and Dehydrofusaric Acid from an Endophytic Fungus //Fusarium// sp. Tlau3. [[http://www.ncbi.nlm.nih.gov/pubmed/22864988#divAbstract|Abstract]]\\ Boonman, N.; Prachya, S., Boonmee, A.; Kittakoop, P.; Wiyakrutta, .S; Sriubolmas, N.; Warit, S.; Chusattayanond, A. D. Planta Med., 2012,78,1562-1567. Adaptogenic-active components from //Kaempferia parviflora// rhizomes. [[http://www.sciencedirect.com/science/article/pii/S0308814611016050#divAbstract|Abstract]]\\ Pripdeevech, P.; Pitija, K.; Rujjanawate, C.; Pojanagaroon, S.; Kittakoop, P.; Wongpornchai, S. Food Chemistry, 2012, 132, 1150-1155. **2011**\\ Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from //Desmos cochinchinensis//. [[http://www.sciencedirect.com/science/article/pii/S003194221100313X#divAbstract|Abstract]]\\ Bajgai, S. P.; Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Phytochemistry, 2011, 72(16), 2062-2067. Longeracemosones A-F, aromatase inhibitors from //Dunbaria longeracemosa//. [[http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100410/abstract#divAbstract|Abstract]]\\ Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S. Eur. J. Org. Chem., 2011, 3803-3808. Nitrogenous sesquiterpenes from the Thai marine sponge //Halichondria// sp. [[http://www.sciencedirect.com/science/article/pii/S0040402011007848#divAbstract|Abstract]]\\ Prawat, H.; Mahidol, C.; Wittayalai, S.; Intachote, P.; Kanchanapoom, T.; Ruchirawat, S. Tetrahedron, 2011, 67(31), 5651-5655. Asperaculin A, a sesquiterpenoid from a marine-derived fungus, //Aspergillus aculeatus//. [[http://pubs.acs.org/doi/abs/10.1021/np200221w#divAbstract|Abstract]]\\ Ingavat, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat Prod., 2011, 74(7), 1650-1652. Protoberberine alkaloids and cancer chemopreventive properties of compounds from //Alangium salviifolium//. [[http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201100423/abstract#divAbstract|Abstract]]\\ Pailee, P.; Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Eur. J. Org. Chem., 2011, 3809-3814. Flavonol 3-//O//-robinobiosides and 3-//O//-(2''-//O//-α-rhamnopyranosyl)-robinobiosides from //Sesuvium portulacastrum//. [[http://www.sciencedirect.com/science/article/pii/S0040402011005485#divAbstract|Abstract]]\\ Disadee, W.; Mahidol, C.; Sahakitpichan, P.; Sitthimonchai, S.; Ruchirawat, S.; Kanchanapoom, T. Tetrahedron, 2011, 67(23), 4221-4226. Itaconic acid derivatives and diketopiperazine from the marine-derived fungus //Aspergillus aculeatus// CRI322-03. [[http://www.sciencedirect.com/science/article/pii/S0031942211000999#divAbstract|Abstract]]\\ Antia, B. S.; Aree, T.; Kasettrathat, C.; Wiyakrutta, S.; Ekpa, O. D.; Ekpe, U. J.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Phytochemistry, 2011, 72(8), 816-820. Unusual glycosides of pyrrole alkaloid and 4'-hydroxyphenylethanamide from leaves of //Moringa oleifera//. [[http://www.sciencedirect.com/science/article/pii/S0031942211001087#divAbstract|Abstract]]\\ Sahakitpichan, P.; Mahidol, C.; Disadee, W.; Ruchirawat, S.; Kanchanapoom, T. Phytochemistry, 2011, 72(8), 791-795. Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus //Colletotrichum// sp. [[http://pubs.acs.org/doi/abs/10.1021/np1003752#divAbstract|Abstract]]\\ Tianpanich, K.; Prachya, S.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat Prod. , 2011, 74(1), 79-81. 3-Hydroxydihydrobenzofuran glucosides from //Gnaphalium polycaulon//. [[https://www.jstage.jst.go.jp/article/cpb/59/9/59_9_1160/_article#divAbstract|Abstract]]\\ Sahakitpichan, P.; Disadee, W.; Ruchirawat, S.; Kanchanapoom, T. Chem. Pharm. Bull. 2011, 59(9), 1160-1162. **2010**\\ Part 1: Antiplasmodial, cytotoxic, radical scavenging and antioxidant activities of Thai plants in the family Acanthaceae. [[http://www.ncbi.nlm.nih.gov/pubmed/20556707#divAbstract|Abstract]]\\ Charoenchai, P.; Vajrodaya, S.; Somprasong ,W.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Planta Medica, 2010, 76, 1940-1943. Curvularides A-E: antifungal hybrid peptide-polyketides from the endophytic fungus //Curvularia geniculate//. [[http://onlinelibrary.wiley.com/doi/10.1002/chem.201000652/abstract#divAbstract|Abstract]]\\ Chomcheon, P.; Wiyakrutta, S.; Aree, T.; Sriubolmas, N.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Chem. Eur. J., 2010, 16, 11178-11185. Variation of sesamin, sesamolin and tocopherols in sesame (//Sesamum indicum// L.) seeds and oil products in Thailand. [[http://openagricola.nal.usda.gov/Record/IND44369814#divAbstract|Abstract]]\\ Rangkadilok, N.; Pholphana, N.; Mahidol, C.; Wongyai, W.; Saengsooksree, K.; Nookabkaew, S.; Satayavivad, J. Food Chemistry, 2010, 122(3), 724-730. Glutarimide alkaloids and a terpenoid benzoquinone from //Cordia globifera//. [[http://pubs.acs.org/doi/abs/10.1021/np100078s?prevSearch=Glutarimide%2Balkaloids%2Band%2Ba%2Bterpenoid%2Bbenzoquinone%2Bfrom%2BCordia%2Bglobifera&searchHistoryKey#divAbstract|Abstract]]\\ Parks, J.; Gyeltshen, T.; Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat Prod., 2010, 73(5), 992-994. α-Glucosidase inhibitory, aromatase inhibitory, and antiplasmodial activities of a biflavonoid GB1 from //Garcinia kola// stem bark. [[https://www.thieme-connect.com/ejournals/abstract/10.1055/s-0029-1186081#divAbstract|Abstract]]\\ Antia, B. S.; Pansanit, A.; Ekpa, O. D.; Ekpe, U. J.; Mahidol, C.; Kittakoop, P. Planta Medica, 2010, 76(3), 276-277. Phytochemical reinvestigation of labdane-type diterpenes and their cytotoxicity from the rhizomes of //Hedychium coronarium//. [[http://www.sciencedirect.com/science/article/pii/S1874390009000561#divAbstract|Abstract]]\\ Chimnoi, N.; Sarasuk, C.; Khunnawutmanotham, N.; Intachote, P.; Seangsai, S.; Saimanee, B.; Pisutjaroenpong, S.; Mahidol, C.; Techasakul, S. Phytochemistry Lett., 2009, 2(4), 184-187. Paraherquamide E. [[http://journals.iucr.org/e/issues/2010/09/00/issconts.html#divAbstract|Abstract]]\\ Aree, T.; Antia, B. S.; Ekpa, O. D.; Kittakoop, P. Acta Cryst., 2010, E66,o2227. An efficient method for selective synthesis of 2-deoxy-2-iodoglycosides by O-glycosylation of D-glucal using I2/Cu(OAc)2. [[http://www.sciencedirect.com/science/article/pii/S0008621510003708#divAbstract|Abstract]]\\ Sirion, U.; Purintawarrakun, S.; Sahakitpichan, P.; Saeeng, R. Carbohydrate Research, 2010, 345(16), 2401-2407. Convertible formation of different glycoside using molecular iodine. [[http://www.heterocycles.jp/newlibrary/payments/form/21528/PDF#divAbstract|Abstract]]\\ Saeeng, R.; Sirion, U.; Sirichan, Y.; Trakulsujaritchok, T.; Sahakitpichan, P. Heterocycles, 2010, 81(11), 2569-2580. //L//-(-)-(//N//-//trans//-Cinnamoyl)-arginine, an acylamino acid from Glinus oppositifolius (L.) Aug. DC. [[http://www.mdpi.com/search?authors=Poolsak+Sahakitpichan#divAbstract|Abstract]]\\ Sahakitpichan, P.; Disadee, W.; Ruchirawat, S.; Kanchanapoom, T. Molecules, 2010, 15, 6186-6192. **2009**\\ Aspergillusol A, an α-Glucosidase Inhibitor from the Marine-Derived Fungus //Aspergillus aculeatus//. [[http://pubs.acs.org/doi/abs/10.1021/np9003883?prevSearch=Aspergillusol%2BA&searchHistoryKey#divAbstract|Abstract]]\\ Ingavat, N.; Dobereiner, J.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat Prod., 2009, 72(11), 2049-2052. Bioactive scalaranes from the Thai Sponge //Hyrtios gumminae//. [[http://pubs.acs.org/doi/abs/10.1021/np900267v?prevSearch=Bioactive%2Bscalaranes%2Bfrom%2Bthe%2BThai%2BSponge%2BHyrtios%2Bgumminae.&searchHistoryKey=#divAbstract|Abstract]]\\ Ingavat, N.; Dobereiner, J.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat Prod., 2009, 72(11), 2049-2052. Aromatase inhibitory, radical scavenging, and antioxidant activities of depsidones and diaryl ethers from the endophytic fungus //Corynespora cassiicola// L36. [[http://www.ncbi.nlm.nih.gov/pubmed/19230943#divAbstract|Abstract]]\\ Chomcheon, P.; Wiyakrutta, S.; Sriubolmas, N.; Ngamrojanavanich, N.; Kengtong, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Phytochemistry, 2009, 70(3), 407-413. Metabolites from the endophytic mitosporic //Dothideomycete// sp. LRUB20. [[http://www.ncbi.nlm.nih.gov/pubmed/19038408#divAbstract|Abstract]]\\ Chomcheon, P.; Wiyakrutta, S.; Sriubolmas, N.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Phytochemistry, 2009, 70(1), 121-127. Labdane diterpenes from the rhizomes of //Hedychium coronarium//. [[http://www.tandfonline.com/doi/full/10.1080/14786410701726434#divAbstract|Abstract]]\\ Chimnoi, N.; Pisutjaroenpong, S.; Ngiwsara, L.; Dechtrirut, D.; Chokchaichamnankit, D.; Khunnawutmanotham, N.; Mahidol, C.; Techasakul, S. Natural Product Research, 2008, 22(14), 1249-1256. Roles of key residues specific to cyclooxygenase II: an ONIOM study. [[http://link.springer.com/article/10.1007/s00706-009-0194-7=#divAbstract|Abstract]]\\ Sae-Tang, D.; Kittakoop, P.; Hannongbua, S. Monatsh. Chem., 2009, 140: 1533-1541. (//E//)-2,4,7-Trichloro-3-hydroxy-8-methoxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo[//b,e//][1,4]dioxepin-11-one monohydrate (nidulin monohydrate). [[http://journals.iucr.org/e/issues/2009/10/00/issconts.html#divAbstract|Abstract]]\\ Aree, T.; Surerum, S.; Ngamrojanavanich, N.; Kittakoop, P. Acta Cryst., 2009, E65, o2470-o2471. In Vitro Screening for Anthelmintic and Antitumour Activity of Ethnomedicinal Plants from Thailand. [[http://www.sciencedirect.com/science/article/pii/S0378874109001500#divAbstract|Abstract]]\\ Atjanasuppat , K.; Wongkham, W.; Meepowpan, P.; Kittakoop, P.; Sobhon, P.; Bartlett, A.; Whitfield, P.J. J. Ethnopharmacol., 2009, 123, 475-482. Biomimetic transformation and biological activities of globiferin, a terpenoid benzoquinone from //Cordia globifera//. [[http://pubs.acs.org/doi/abs/10.1021/np9000703?prevSearch=Cordia%2Bglobifera&searchHistoryKey#divAbstract|Abstract]]\\ Dettrakul, S.; Surerum, S.; Rajviroongit, S.; Kittakoop, P. J. Nat. Prod., 2009, 72, 861-865. A new synthetic approach towards isoquinobenzazepinone and isoindolinobenzazepinone using acid-mediated cyclisation and Heck reaction. [[http://www.sciencedirect.com/science/article/pii/S0040402008018346#divAbstract|Abstract]]\\ Phakhodee, W.; Ploypradith, P.; Sahakitpichan, P.; Ruchirawat, S. Tetrahedron, 2009, 65, 351-356. **2008**\\ Labdane diterpenes from the rhizome of //Hedychium coronarium//.[[http://www.ncbi.nlm.nih.gov/pubmed/18932088|abstract]]\\ Chimnoi N, Pisutcharoenpong S, Ngiwsara L, Dechtrirut D, Chokchaichamnankit D, Khunnawutmanotham N, Mahidol C, Techasakul S\\ Nat Prod Res 2008;22(14):1255-1262. Cytotoxic and antiplasmodial substances from marine-derived fungi, //Nodulisporium// sp. and CRI247-01.[[http://www.sciencedirect.com/science/article/pii/S0031942208003634|abstract]]\\ Kasettrathat, C.; Ngamrojanavanich, N.; Wiyakrutta, S.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Phytochemistry, 2008, 69(14), 2621-2626. Diketopiperazines and phthalides from a marine derived fungus of the order Pleosporales.[[https://www.thieme-connect.de/ejournals/abstract/10.1055/s-2007-993783|abstract]]\\ Prachyawarakorn, V.; Mahidol, C.; Sureram, S.; Sangpetsiripan, S.; Wiyakrutta, S.; Ruchirawat, S.; Kittakoop, P. Planta Med., 2008, 74(1), 69-72. A new synthetic approach towards isoquinobenzazepinone and soindolinobenzazepinone using acid-mediated cyclization and Heck reaction. [[http://www.sciencedirect.com/science/article/pii/S0040402008018346|abstract]]\\ Phakhodee, W.; Ploypradith, P.; Sahakitpichan, P.; Ruchirawat, S. Tetrahedron, 2008, 65(1), 351-356. Investigation of the acid-mediated cyclisation of amide acetal for the synthesis of benzazepinone.[[http://www.heterocycles.jp/newlibrary/libraries/journal/75/8|abstract]]\\ Phakhodee, W.; Sahakitpichan, P.; Deechongkit, S.; Ruchirawat, S. Heterocycles, 2008, 75(8), 1963-1970. Functional group-mediated biotransformation by //Curvularia lunata// NRRL 2178: synthesis of 3-dehydro-2-deoxyecdysteroids from the 3-hydroxy-2-mesyloxy analogues.[[http://www.sciencedirect.com/science/article/pii/S0040402008000148|abstract]]\\ Changtam, C.; Sukcharoen, O.; Yingyongnarongkul, B.; Chimnoi, N.; Suksamrarn, A.Tetrahedron, 2008, 64(11), 2626-2633. **2007**\\ Diterpenoids from the roots of //Croton oblongifolius//.[[https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2007-990247|abstract]]\\ Youngsa-ad, W.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Prawat, H.; Kittakoop, P. Planta Med., 2007, 73(14), 1491-1494. Cytotoxic mycoepoxydiene derivatives from an endophytic fungus //Phomopsis// sp. isolated from //Hydnocarpus anthelminthicus//.[[https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2007-990240|abstract]]\\ Prachya, S.; Wiyakrutta, S.; Sriubolmas, N.; Ngamrojanavanich, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. Planta Med., 2007, 73(13), 1418-1420. Regioisomers of acylcoumarins from the flowers of// Mammea siamensis//.\\ Mahidol, C.; Prawat, H.; Kaweetripob, W.; Ruchirawat, S. Natural Product Communications, 2007, 2(5), 557-564. Bioactive compounds from //Bauhinia purpurea// possessing antimalarial, antimycobacterial, antifungal, antiinflammatory, and cytotoxic activities.[[ http://pubs.acs.org/doi/abs/10.1021/np070010e|abstract]]\\ Boonphong, S.; Puangsombat, P.; Baramee, A.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat. Prod., 2007, 70(5), 795-801. Novel 2-chloro-8-arylthiomethyldipyridodiazepinone derivatives with activity against HIV-1 reverse transcriptase.[[http://www.mdpi.com/1420-3049/12/2/218|abstract]]\\ Khunnawutmanotham, N., Chimnoi, N., Pungpo, P., Louisirirotchanakul, S., Hannongbua, S., Techasakul, S. Molecules 2007;12:218-30. **2006**\\ Cyclopentenones, Scaffolds for Organic Syntheses Produced by the Endophytic Fungus Mitosporic //Dothideomycete// sp. LRUB20. [[http://pubs.acs.org/doi/abs/10.1021/np060148h|abstract]]\\ Chomcheon, P.; Sriubolmas, N.; Wiyakrutta, S.; Ngamrojanavanich, N.; Chaichit, N.; Mahidol, C.; Ruchirawat, S.; Kittakoop, P. J. Nat. Prod., 2006, 69(9), 1351-1353. Siamenols A-D, four new coumarins from //Mammea siamensis//. [[https://www.jstage.jst.go.jp/article/cpb/54/6/54_6_884/_article|abstract]]\\ Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S. Chem. Pharm. Bull., 2006, 54(6), 884-886. Pyranocoumarins from the twigs of //Mammea siamensis//.[[http://www.sciencedirect.com/science/article/pii/S0031942206001051|abstract]]\\ Prachyawarakorn, V.; Mahidol, C.; Ruchirawat, S. Phytochemistry, 2006, 67(9), 924-928. Total Synthesis of Natural and Unnatural Lamellarins with Saturated and Unsaturated D-Rings.>[[ http://pubs.acs.org/doi/abs/10.1021/jo061810h|abstract]]\\ By Ploypradith, P.; Petchmanee, T.; Sahakitpichan, P.; Litvinas, N. D.; Ruchirawat, S. J. Org. Chem., 2006, 71(25), 9440-9448. Cytotoxic prenylated xanthones om the young uit of //Garcinia mangostana//.[[ https://www.jstage.jst.go.jp/article/cpb/54/3/54_3_301/_article|abstract]]\\ Suksamrarn, S.; Komutiban, O.; Ratananukul, P.; Chimnoi, N.; Lartpornmatulee, N.; Suksamrarn, A. Chem. Pharm. Bull., 2006, 54(3), 301-305 **2005**\\ Environmental biotechnology for developing countries: needs and priorities. [[http://link.springer.com/article/10.1007/s10295-005-0058-z/fulltext.html|abstract]]\\ Mahidol, C. Journal of Industrial Microbiology & Biotechnology, 2005, 32(11-12), 492-495. Oxygenated Pimarane Diterpenes from //Kaempferia marginata//. [[http://pubs.acs.org/doi/abs/10.1021/np050186l|abstract]]\\ Thongnest, S.; Mahidol, C.; Sutthivaiyakit, S.; Ruchirawat, S. J. Nat. Prod., 2005, 68(11), 1632-1636. Proteomic profiling of cholangiocarcinoma cell line treated with pomiferin from //Derris malaccensis//.[[http:// http://onlinelibrary.wiley.com/doi/10.1002/pmic.200401315/abstract|abstract]]\\ Svasti, J.; Srisomsap, C.; Subhasitanont, P.; Keeratichamroen, S.; Chokchaichamnankit, D.; Ngiwsara, L.; Chimnoi, N.; Pisutjaroenpong, S.; Techasakul, S.; Chen, S.-T. Proteomics (2005), 5(17), 4504-4509. Constituents of the leaves of //Macaranga tanarius//.[[http://pubs.acs.org/doi/abs/10.1021/np0500272|abstract]]\\ Phommart, S.; Sutthivaiyakit, P.; Chimnoi, N.; Ruchirawat, S.; Sutthivaiyakit, S. J. Nat. Prod., 2005, 68(6), 927-930. **2004**\\ A highly efficient synthesis of lamellarins K and L by the Michael addition/ring-closure reaction of benzyldihydroisoquinoline derivatives with ethoxycarbonyl--nitrostyrenes. [[http://onlinelibrary.wiley.com/doi/10.1002/anie.200352043/abstract|abstract]]\\ Ploypradith, P.; Mahidol, C.; Sahakitpichan, P.; Wongbundit, S.; Ruchirawat, S. Angewandte Chemie, International Edition, 2004, 43(7), 866-868. Malaria: integrated approaches for prevention and treatment.\\ Mahidol, C. Acta tropica, 2004, 89(3), 265-269. Efficient synthesis of diospyrol via Suzuki-Miyaura and modified in situ cross-coupling. [[https://www.thieme-connect.com/ejournals/abstract/10.1055/s-2005-872176|abstract]]\\ Sahakitpichan, P.; Thasana, N.; Ruchirawat, S. Synthesis, 2005, (17), 2934-2938. A practical and highly efficient synthesis of lennoxamine and related isoindolobenzazepines. [[http://www.sciencedirect.com/science/article/pii/S0040402004004399|abstract]]\\ Sahakitpichan, P.; Ruchirawat, S. Tetrahedron, 2004, 60(19), 4169-4172. Stereoselective synthesis and moulting activity of 2,3-diepi-20-hydroxyecdysone and 2,3-diepi-5-20-hydroxyecdysone.[[http://www.sciencedirect.com/science/article/pii/S0040402004002984|abstract]]\\ Homvisasevongsa, S.; Chuaynugul, A.; Chimnoi, N.; Suksamrarn, A. 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