Laboratory of Biochemistry

Aberrant O-GlcNAc-modified proteins expressed in primary colorectal cancer.
Phueaouan T, Chaiyawat P, Netsirisawan P, Chokchaichamnankit D, Punyarit P, Srisomsap C, Svasti J, Champattanachai V
Oncol Rep30p2929-36(2013 Dec)

Comparative proteomic analysis of oral squamous cell carcinoma and adjacent non-tumour tissue from Thailand.
Chanthammachat P, Promwikorn W, Pruegsanusak K, Roytrakul S, Srisomsap C, Chokchaichamnankit D, Svasti J, Boonyaphiphat P, K S, Thongsuksai P
Arch Oral Biol58p1677-85(2013 Nov)

Proteomic analysis reveals important role of 14-3-3σ in anoikis resistance of cholangiocarcinoma cells.
Khongmanee A, Lirdprapamongkol K, Tit-Oon P, Chokchaichamnankit D, Svasti J, Srisomsap C
Proteomicsp(2013 Sep 12)

A flavonoid chrysin suppresses hypoxic survival and metastatic growth of mouse breast cancer cells.
Lirdprapamongkol K, Sakurai H, Abdelhamed S, Yokoyama S, Maruyama T, Athikomkulchai S, Viriyaroj A, Awale S, Yagita H, Ruchirawat S, Svasti J, Saiki I
Oncol Rep30p2357-64(2013 Nov)

Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation.
Lirdprapamongkol K, Sakurai H, Abdelhamed S, Yokoyama S, Athikomkulchai S, Viriyaroj A, Awale S, Ruchirawat S, Svasti J, Saiki I
Int J Oncol43p329-37(2013 Jul)

Proteomic analysis and abrogated expression of O-GlcNAcylated proteins associated with primary breast cancer.
Champattanachai V, Netsirisawan P, Chaiyawat P, Phueaouan T, Charoenwattanasatien R, Chokchaichamnankit D, Punyarit P, Srisomsap C, Svasti J
Proteomics13p2088-99(2013 Jul)

Role of curcuminoids in ameliorating oxidative modification in β-thalassemia/Hb E plasma proteome.
Weeraphan C, Srisomsap C, Chokchaichamnankit D, Subhasitanont P, Hatairaktham S, Charoensakdi R, Panichkul N, Siritanaratkul N, Fucharoen S, Svasti J, Kalpravidh RW
J Nutr Biochem24p578-85(2013 Mar)

Decreasing activity and altered protein processing of human iduronate-2-sulfatase mutations demonstrated by expression in COS7 cells.
Charoenwattanasatien R, Cairns JR, Keeratichamroen S, Sawangareetrakul P, Tanpaiboon P, Wattanasirichaigoon D, Pangkanon S, Svasti J, Champattanachai V
Biochem Genet50p990-7(2012 Dec)

Curcumin resistance induced by hypoxia in HepG2 cells is mediated by multidrug-resistance-associated proteins.
Sakulterdkiat T, Srisomsap C, Udomsangpetch R, Svasti J, Lirdprapamongkol K
Anticancer Res32p5337-42(2012 Dec)

Studies of the in vitro cytotoxic, antioxidant, lipase inhibitory and antimicrobial activities of selected Thai medicinal plants.
Kaewpiboon C, Lirdprapamongkol K, Srisomsap C, Winayanuwattikun P, Yongvanich T, Puwaprisirisan P, Svasti J, Assavalapsakul W
BMC Complement Altern Med12p217(2012 Nov 13)

Paclitaxel delivery using carrier made from curcumin derivative: synergism between carrier and the loaded drug for effective cancer treatment.
Amornwachirabodee K, Chiablaem K, Wacharasindhu S, Lirdprapamongkol K, Svasti J, Vchirawongkwin V, Wanichwecharungruang SP
J Pharm Sci101p3779-86(2012 Oct)

Effective enrichment of cholangiocarcinoma secretomes using the hollow fiber bioreactor culture system.
Weeraphan C, Diskul-Na-Ayudthaya P, Chiablaem K, Khongmanee A, Chokchaichamnankit D, Subhasitanont P, Svasti J, Srisomsap C
Talanta99p294-301(2012 Sep 15)

Clinical and molecular findings in Thai patients with isolated methylmalonic acidemia.
Vatanavicharn N, Champattanachai V, Liammongkolkul S, Sawangareetrakul P, Keeratichamroen S, Ketudat Cairns JR, Srisomsap C, Sathienkijkanchai A, Shotelersuk V, Kamolsilp M, Wattanasirichaigoon D, Svasti J, Wasant P
Mol Genet Metab106p424-9(2012 Aug)

Exploring stemness gene expression and vasculogenic mimicry capacity in well- and poorly-differentiated hepatocellular carcinoma cell lines.
Lirdprapamongkol K, Chiablaem K, Sila-Asna M, Surarit R, Bunyaratvej A, Svasti J
Biochem Biophys Res Commun422p429-35(2012 Jun 8)

Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts.
Sriiam S, Leecharoenkiat A, Lithanatudom P, Wannatung T, Svasti S, Fucharoen S, Svasti J, Chokchaichamnankit D, Srisomsap C, Smith DR
Blood Cells Mol Dis48p77-85(2012 Feb 15)

Increased oxidative metabolism is associated with erythroid precursor expansion in β0-thalassaemia/Hb E disease.
Leecharoenkiat A, Wannatung T, Lithanatudom P, Svasti S, Fucharoen S, Chokchaichamnankit D, Srisomsap C, Smith DR
Blood Cells Mol Dis47p143-57(2011 Oct 15)

A proteomic analysis of Curcuma comosa Roxb. rhizomes.
Boonmee A, Srisomsap C, Chokchaichamnankit D, Karnchanatat A, Sangvanich P
Proteome Sci9p43(2011 Jul 29)

Differential protein expression in primary breast cancer and matched axillary node metastasis.
Thongwatchara P, Promwikorn W, Srisomsap C, Chokchaichamnankit D, Boonyaphiphat P, Thongsuksai P
Oncol Rep26p185-91(2011 Jul)

Overcoming Multidrug Resistance in Human Lung Cancer with Novel Benzo[a]quinolizin-4-ones.
Kanintronkul Y, Worayuthakarn R, Thasana N, Winayanuwattikun P, Pattanapanyasat K, Surarit R, Ruchirawat S, Svasti J
Anticancer Res31p921-7(2011 Mar)

Proteomic analysis of Chinese kale (B. alboglabra) leaves during growth.
Zuraifah Asrah Mohamad, Daranee Chokchaichamnankit, Kisana Bhinija, N. Monique Paricharttanakul, Jisnuson Svasti, Pattana Srifah Huehne, Chantragan Srisomsap
Journal of Integrated OMICS 1 (1) p102-107 (2011)

Mucoadhesive curcumin nanospheres: Biological activity, adhesion to stomach mucosa and release of curcumin into the circulation.
Suwannateep N, Banlunara W, Wanichwecharungruang SP, Chiablaem K, Lirdprapamongkol K, Svasti J
J Control Releasep(2011 Jan 15)

An antioxidant protein in Curcuma comosa Roxb. Rhizomes.
Boonmee, A., Srisomsap, C., Karnchanatat, A. and Sangvanich, P.
Food Chemistry 124 (2) p476-480 (2011)

Eco-friendly synthesis of fucoidan-stabilized gold nanoparticles.
Soisuwan, S., Warisnoicharoen, W., Lirdprapamongkol, K. and Svasti, J.
American Journal of Applied Sciences 7 (8) p1038-1042 (2010)

Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells.
Banjerdpongchai R, Kongtawelert P, Khantamat O, Srisomsap C, Chokchaichamnankit D, Subhasitanont P, Svasti J
J Hematol Oncol3p50(2010 Dec 30)

Proteomic studies of cholangiocarcinoma and hepatocellular carcinoma cell secretomes.
Srisomsap C, Sawangareetrakul P, Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Bhudhisawasdi V, Wongkham S, Svasti J
J Biomed Biotechnol2010p437143(2010)

Metabolic alteration of HepG2 in scaffold-based 3-D culture: proteomic approach.
Pruksakorn D, Lirdprapamongkol K, Chokchaichamnankit D, Subhasitanont P, Chiablaem K, Svasti J, Srisomsap C
Proteomics10p3896-904(2010 Nov)

Complete amino acid sequence of three reptile lysozymes.
Ponkham P, Daduang S, Kitimasak W, Krittanai C, Chokchaichamnankit D, Srisomsap C, Svasti J, Kawamura S, Araki T, Thammasirirak S
Comp Biochem Physiol C Toxicol Pharmacol151p75-83(2010 Jan)

Vanillin enhances TRAIL-induced apoptosis in cancer cells through inhibition of NF-kappaB activation.
Lirdprapamongkol K, Sakurai H, Suzuki S, Koizumi K, Prangsaengtong O, Viriyaroj A, Ruchirawat S, Svasti J, Saiki I
In Vivo24p501-6(2010 Jul-Aug)

Comparative proteomic analysis of lung cancer cell line and lung fibroblast cell line.
Rubporn A, Srisomsap C, Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Svasti J, Sangvanich P
Cancer Genomics Proteomics6p229-37(2009 Jul-Aug)

Vanillin suppresses metastatic potential of human cancer cells through PI3K inhibition and decreases angiogenesis in vivo.
Lirdprapamongkol K, Kramb JP, Suthiphongchai T, Surarit R, Srisomsap C, Dannhardt G, Svasti J
J Agric Food Chem57p3055-63(2009 Apr 22)

Proteomic alterations during dormant period of Curcuma longa rhizomes.
Chokchaichamnankit, D., Subhasitanont, P., Paricharttanakul, NM., Sangvanich, P., Svasti, J. and Srisomsap, C.
Journal of Proteomics and Bioinformatics 2(9) p380-387 (2009)

Juice of eclipta prostrata inhibits cell migration in vitro and exhibits anti-angiogenic activity in vivo.
Lirdprapamongkol K, Kramb JP, Chokchaichamnankit D, Srisomsap C, Surarit R, Sila-Asna M, Bunyaratvej A, Dannhardt G, Svasti J
In Vivo22p363-8(2008 May-Jun)

Molecular analysis of the iduronate-2-sulfatase gene in Thai patients with Hunter syndrome.
Keeratichamroen S, Ketudat Cairns JR, Wattanasirichaigoon D, Wasant P, Ngiwsara L, Suwannarat P, Pangkanon S, Kuptanon J, Tanpaiboon P, Rujirawat T, Liammongkolkul S, Svasti J
J Inherit Metab Disp(2008 May 20)

Galectin-3 expression in human papillary thyroid carcinoma.
Sawangareetrakul P, Srisomsap C, Chokchaichamnankit D, Svasti J
Cancer Genomics Proteomics5p117-22(2008 Mar-Apr)

Molecular characterization of type 3 (neuronopathic) Gaucher disease in Thai patients.
Suwannarat P, Keeratichamroen S, Wattanasirichaigoon D, Ngiwsara L, Cairns JR, Svasti J, Visudtibhan A, Pangkanon S
Blood Cells Mol Dis39p348-52(2007 Nov-Dec)

Novel mutations found in two genes of thai patients with isolated methylmalonic acidemia.
Keeratichamroen S, Cairns JR, Sawangareetrakul P, Liammongkolkul S, Champattanachai V, Srisomsap C, Kamolsilp M, Wasant P, Svasti J
Biochem Genet45p421-30(2007 Jun)

Comparison of membrane-associated proteins in human cholangiocarcinoma and hepatocellular carcinoma cell lines.
Srisomsap C, Subhasitanont P, Sawangareetrakul P, Chokchaichamnankit D, Ngiwsara L, Chiablaem K, Svasti J
Proteomics Clin Appl1p89-106(2007 Jan)

Hemagglutinating activity of Curcuma plants.
Sangvanich P, Kaeothip S, Srisomsap C, Thiptara P, Petsom A, Boonmee A, Svasti J
Fitoterapia78p29-31(2007 Jan)

New variant of quail egg white lysozyme identified by peptide mapping.
Thammasirirak S, Preecharram S, Ponkham P, Daduang S, Araki T, Svasti J
Comp Biochem Physiol B Biochem Mol Biol147p314-24(2007 Jun)

Clinical and molecular characterization of an extended family with Fabry disease.
Wattanasirichaigoon D, Svasti J, Cairns JR, Tangnararatchakit K, Visudtibhan A, Keeratichamroen S, Ngiwsara L, Khowsathit P, Onkoksoong T, Lekskul A, Mongkolsiri D, Jariengprasert C, Thawil C, Ruencharoen S
J Med Assoc Thai89p1528-35(2006 Sep)

Proteomic studies of galectin-3 expression in human thyroid diseases by immunodetection.
Subhasitanont, P., Srisomsap, C., Punyarit, P. and Svasti, J.
Cancer Genomics Proteomics 3 (6) p389-394 (2006)

Purification, characterization and comparison of reptile lysozymes.
Thammasirirak S, Ponkham P, Preecharram S, Khanchanuan R, Phonyothee P, Daduang S, Srisomsap C, Araki T, Svasti J
Comp Biochem Physiol C Toxicol Pharmacol143p209-17(2006 Jun)

Chicken egg yolk antibodies specific for the gamma chain of human hemoglobin for diagnosis of thalassemia.
Jintaridth P, Srisomsap C, Vichittumaros K, Kalpravidh RW, Winichagoon P, Fucharoen S, Jisnuson Svasti MR, Kasinrerk W
Int J Hematol83p408-14(2006 Jun)

Proteomic profiling of cholangiocarcinoma cell line treated with pomiferin from Derris malaccensis.
Svasti J, Srisomsap C, Subhasitanont P, Keeratichamroen S, Chokchaichamnankit D, Ngiwsara L, Chimnoi N, Pisutjaroenpong S, Techasakul S, Chen ST
Proteomics5p4504-9(2005 Nov)

The molecular basis of mucopolysaccharidosis type I in two Thai patients.
Ketudat Cairns JR, Keeratichamroen S, Sukcharoen S, Champattanachai V, Ngiwsara L, Lirdprapamongkol K, Liammongkolkul S, Srisomsap C, Surarit R, Wasant P, Svasti J
Southeast Asian J Trop Med Public Health36p1308-12(2005 Sep)

Hb Kurosaki [alpha7(A5)Lys -->Glu (AAG --> GAG)]: an alpha2-globin gene mutation found in Thailand.
Ngiwsara L, Srisomsap C, Winichagoon P, Fucharoen S, Sae-Ngow B, Svasti J
Hemoglobin29p155-9(2005)

Argininosuccinate synthetase deficiency: mutation analysis in 3 Thai patients.
Wasant P, Viprakasit V, Srisomsap C, Liammongkolkul S, Ratanarak P, Sathienkijakanchai A, Svasti J
Southeast Asian J Trop Med Public Health36p757-61(2005 May)

Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells.
Lirdprapamongkol K, Sakurai H, Kawasaki N, Choo MK, Saitoh Y, Aozuka Y, Singhirunnusorn P, Ruchirawat S, Svasti J, Saiki I
Eur J Pharm Sci25p57-65(2005 May)

Proteomic analysis of cholangiocarcinoma cell line.
Srisomsap C, Sawangareetrakul P, Subhasitanont P, Panichakul T, Keeratichamroen S, Lirdprapamongkol K, Chokchaichamnankit D, Sirisinha S, Svasti J
Proteomics4p1135-44(2004 Apr)

Two cases of compound heterozygosity for Hb Hekinan [alpha27(B8)Glu-->Asp (alpha1)] and alpha-thalassemia in Thailand.
Ngiwsara L, Srisomsap C, Winichagoon P, Fucharoen S, Svasti J
Hemoglobin28p145-50(2004 May)

Novel mutations in a Thai patient with methylmalonic acidemia.
Champattanachai V, Ketudat Cairns JR, Shotelersuk V, Keeratichamroen S, Sawangareetrakul P, Srisomsap C, Kaewpaluek V, Svasti J
Mol Genet Metab79p300-2(2003 Aug)

Hb Kodaira II [beta146(HC3)His --> Gln] detected in Thailand.
Ngiwsara L, Srisomsap C, Winichagoon P, Fucharoen S, Svasti J
Hemoglobin27p37-9(2003 Feb)

Hb Siam [alpha15(A13)Gly-->Arg (alpha1) (GGT-->CGT)] is a typical alpha chain hemoglobinopathy without an alpha-thalassemic effect.
Turbpaiboon C, Svasti S, Sawangareetakul P, Winichagoon P, Srisomsap C, Siritanaratkul N, Fucharoen S, Wilairat P, Svasti J
Hemoglobin26p77-81(2002 Feb)

Detection of cathepsin B up-regulation in neoplastic thyroid tissues by proteomic analysis.
Srisomsap C, Subhasitanont P, Otto A, Mueller EC, Punyarit P, Wittmann-Liebold B, Svasti J
Proteomics2p706-12(2002 Jun)

Urea cycle disorders in Thai infants: a report of 5 cases.
Wasant P, Srisomsap C, Liammongkolkul S, Svasti J
J Med Assoc Thai85 Suppl 2pS720-31(2002 Aug)

Double heterozygosity for Hb Pyrgos [beta83(EF7)Gly-->Asp] and Hb E [beta26(B8)Glu-->Lys] found in association with alpha-thalassemia.
Sawangareetrakul P, Svasti S, Yodsowon B, Winichagoon P, Srisomsap C, Svasti J, Fucharoen S
Hemoglobin26p191-6(2002 May)

Inherited metabolic disorders in Thailand.
Wasant P, Svasti J, Srisomsap C, Liammongkolkul S
J Med Assoc Thai85 Suppl 2pS700-9(2002 Aug)