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Laboratory of Medicinal Chemistry

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Recent Publications (2008 - present)

  1. Tangdenpaisal K, Ruchirawat S, Ploypradith P. Synthesis of the Thyroid Hormone Analog GC-1 via Bi(OTf)3-Catalyzed Benzylation. Tetrahedron 2014; 70: in press. Abstract
  2. Tummatorn J, Krajangsri S, Norseeda K, Thongsornkleeb C, Ruchirawat S. A New Synthetic Approach to 6-Unsubstituted Phenanthridine and Phenanthridine-like Compounds under Mild and Metal-free Conditions. Org. Biomol. Chem. 2014; 12: 5077-5081. Abstract
  3. Tummatorn J, Gleeson MP, Krajangsri S, Thongsornkleeb C, Ruchirawat S. ZrCl4-Promoted Facile Synthesis of Indole Derivatives. RSC Adv. 2014; 4: 20048–20052. Abstract
  4. Worayuthakarn R, Boonya-udtayan S, Ruchirawat S, Thasana N. Total Synthesis of Unsymmetrical Benzils, Scandione and Calophione A. Eur. J. Org. Chem. 2014; (12): 2496-2507. Abstract
  5. Nealmongkol P, Tangdenpaisal K, Ruchirawat S, Thasana N. Cu(I)-mediated Lactone Formation in Subcritical Water: A Benign Synthesis of Benzopyranones and Urolithins A-C. Tetrahedron 2013; 69: 9277-9283. Abstract
  6. Sarnpitak P, Trongchit K, Kostenko Y, Sathalalai S, Gleeson MP, Ruchirawat S, Ploypradith P. Synthesis of Substituted 2-Arylindanes from E-(2-Stilbenyl)methanols via Lewis acid-mediated Cyclization and Nucleophililc Transfer from Trialkylsilyl Reagents. J. Org. Chem. 2013; 78: 8281-8296. Abstract
  7. Tummatorn J, Thongsornkleeb C, Ruchirawat S, Gettongsong T. Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Ethyl Esters from Arylmethyl Azides via a Domino Process. Org. Biomol. Chem. 2013; 11: 1463-1467. Abstract
  8. Tangdenpaisal K, Phakhodee W, Ruchirawat S, Ploypradith P. Facile Synthesis of Diarylmethanes via Quinone Methides. Tetrahedron 2013; 69: 933-941. Abstract
  9. Boonya-Udtayan S, Eno M, Ruchirawat S, Mahidol C, Thasana N. Palladium-Catalyzed Intramolecular C-H Amidation: Synthesis and Biological Activities of Indolobenzazocin-8-ones. Tetrahedron 2012; 68: 10293-10301. Abstract
  10. Tummatorn J, Thongsornkleeb C, Ruchirawat S. Acid-Promoted Rearrangement of Arylmethyl Azides: Applications toward the Synthesis of N-Arylmethyl Arenes and Polycyclic Heteroaromatic Compounds. Tetrahedron 2012; 68: 4732-4739. Abstract
  11. Worayuthakarn R, Nealmongkol P, Ruchirawat S, Thasana N. Synthesis of Benzoindoloquinolizines via a Cu(I)-mediated C-N Bond Formation. Tetrahedron 2012; 68: 2864-2875. Abstract
  12. Wittayalai S, Sathalalai S, Thorroad S, Worawittayanon P, Ruchirawat S, Thasana N. Lycophlegmariols A-D: Cytotoxic Serratene Triterpenoids from the Club Moss Lycopodium phlegmaria L. Phytochemistry 2012; 76: 117-123. Abstract
  13. Disadee W, Ploypradith P, Aree T, Chaichit N, Ruchirawat S. A Novel Approach for the Synthesis of Lophocladines A, B and C1 Analogues. Tetrahedron Lett. 2011; 52: 6142-6144. Abstract
  14. Radomkit S, Sarnpitak P, Tummatorn J, Batsomboon P, Ruchirawat S, Ploypradith P. Pt(IV)-catalyzed Generation and [4+2]-Cycloaddition Reactions of O-Quinone Methides. Tetrahedron 2011; 67: 3904-3914. Abstract
  15. Gleeson MP, Deechongkit S, Ruchirawat S. Molecular Dynamics Investigation of Psalmopeotoxin I. Probing the Relationship between 3D Structure, Anti-malarial Activity and Thermal Stability. J. Mol. Model. 2011; 17: 769-775. Abstract
  16. Boonya-Udtayan S, Yotapan N, Woo C, Bruns CJ, Ruchirawat S, Thasana N. Synthesis and Biological Activities of Azalamellarins. Chem. Asian J. 2010; 5: 2113-2123. Abstract
  17. Chittchang M, Gleeson MP, Ploypradith P, Ruchirawat S. Assessing the Drug-likeness of Lamellarins, a Marine-derived Natural Product Class with Diverse Oncological Activities. Eur. J. Med. Chem. 2010; 45: 2165-2172. Abstract
  18. Kamolkijkarn P, Prasertdee T, Netirojjanakul C, Sarnpitak P, Ruchirawat S, Deechongkit S. Synthesis, Biophysical, and Biological Studies of Wild-Type and Mutant Psalmopeotoxins-anti-malarial Cysteine Knot Peptides from Psalmopoeus cambridgei. Peptides 2010; 31: 533-540. Abstract
  19. Tummatorn J, Ruchirawat S, Ploypradith P. A Convergent General Strategy for the Functionalized 2-Aryl Cycloalkylfused Chromans: Intramolecular Hetero-Diels-Alder Reactions of ortho-Quinone Methides. Chem. Eur. J. 2010; 16: 1445-1448. Abstract
  20. Tangdenpaisal K, Sualek S, Ruchirawat S, Ploypradith P. Factors Affecting Orthogonality in the Deprotection of 2,4-Di-protected Aromatic Ethers Employing Solid-supported Acids. Tetrahedron 2009; 65: 4316-4325. Abstract
  21. Batsomboon P, Phakhodee W, Ruchirawat S, Ploypradith P. Generation of ortho-Quinone Methides by p-TsOH on Silica and Their Hetero-Diels-Alder Reactions with Styrenes. J. Org. Chem. 2009; 74: 4009-4012. Abstract
  22. Chittchang M, Batsomboon P, Ruchirawat S, Ploypradith P. Cytotoxicities and Structure-activity Relationships of Natural and Unnatural Lamellarins toward Cancer Cell Lines. ChemMedChem 2009; 4: 457-465. Abstract
  23. Phakhodee W, Ploypradith P, Sahakitpichan P, Ruchirawat S. A New Synthetic Approach towards Isoquinobenzazepinone and Isoindolinobenzazepinone using Acid-mediated Cyclisation and Heck Reaction. Tetrahedron 2009; 65: 351-356. Abstract
  24. Worayuthakarn R, Boonya-udtayan S, Arom-oon E, Ploypradith P, Ruchirawat S, Thasana N. Synthesis of Unsymmetrical Benzil Licoagrodione. J. Org. Chem. 2008; 73: 7432-7435. Abstract
  25. Phakhodee W, Sahakitpichan P, Deechongkit S, Ruchirawat S. Investigation of the Acid-mediated Cyclisation of Amide Acetal for the Synthesis of Benzazepinone. Heterocycles 2008; 75: 1963-1970. Abstract
  26. Thasana N, Bjerke-Kroll B, Ruchirawat S. A Facile Synthesis of Telisatin A via Microwave-promoted Annulation and Reformatsky Reaction. Synlett 2008; 505-508. Abstract

Publications from Collaborations

  1. Maibunkaew T, Thongsornkleeb C, Tummatorn J, Bunrit A, Ruchirawat S. Practical and Metal-free Electrophilic Aromatic Halogenation by Inter­halogen Compounds Generated in situ from N-Halosuccinimide and Catalytic TMSCl. Synlett 2014; 25: 1769-1775. Abstract
  2. Sahakitpichan P, Mahidol C, Disadee W, Chimnoi N, Ruchirawat S, Kanchanapoom T. Glucopyranosyloxybenzyl Derivatives of (R)-2-Benzylmalic Acid and (R)-Eucomic Acid, and an Aromatic Glucoside from the Pseudobulbs of Grammatophyllum speciosum. Tetrahedron 2013; 69: 1031-1037. Abstract
  3. Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis and Cytotoxicity of Novel N-Sulfonyl-1,2,3,4-tetrahydroisoquinoline Thiosemicarbazone Derivatives. Med. Chem. Res. 2013; 22: 267-277. Abstract
  4. Phakeovilay C, Disadee W, Sahakitpichan P, Sitthimonchai S, Kittakoop P, Ruchirawat S, Kanchanapoom T. Phenylethanoid and Flavone Glycosides from Ruellia tuberosa L. J. Nat. Med. 2013; 67: 228-233. Abstract
  5. Boonyarattanakalin S, Ruchirawat S, Gleeson MP. Ring Opening Polymerization of Mannosyl Tricyclic Orthoesters: Rationalising The Stereo and Regioselectivity of Glycosidic Bond Formation using Quantum Chemical Calculations. Med. Chem. Commun. 2013; 4: 265-268. Abstract
  6. Pingaew R, Tongraung P, Worachartcheewan A, Nantasenamat C, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Cytotoxicity and QSAR Study of (Thio)ureas Derived from Phenylalkylamines and Pyridylalkylamines. Med. Chem. Res. 2012: DOI 10.1007/s00044-012-0402-6. Abstract
  7. Thongsornkleeb C, Rabten W, Bunrit A, Tummatorn J, Ruchirawat S. Facile Access to 2,5-Disubstituted-4-chloromethyl-3-iodofuran Derivatives via ICl-Mediated Cyclization of 1-Alkyl-2-alkynylallylic Alcohols. Tetrahedron Lett. 2012; 53: 6615-6619. Abstract
  8. Prachayasittikul S, Pingaew R, Yamkamon U, Worachartcheewan A, Wanwimolruk S, Ruchirawat S, Prachayasittikul V. Chemical Constituents and Antioxidant Activity of Hydnophytum formicarum Jack. Int. J. Pharmacol. 2012; 8: 440-444. Abstract
  9. Siripong P, Yahuafai J, Piyaviriyakul S, Kanokmedhakul K, Koide H, Ishii T, Shimizu K, Ruchirawat S, Oku N. Inhibitory Effect of Liposomal Rhinacanthin-N Isolated from Rhinacanthus nasutus on Pulmonary Metastasis in Mice. Biol. Pharm. Bull. 2012; 35: 1197-1200. Abstract
  10. Pingaew R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Synthesis and Cytotoxicity of Novel 2,2'-Bis- and 2,2',2''-Tris-indolyl-methanes-based Bengacarboline Analogs. Arch. Pharm. Res. 2012; 35: 949-954. Abstract
  11. Prachayasittikul S, Worachartcheewan A, Pingaew R, Suksrichavalit T, Isarankura-Na-Ayudhya C, Ruchirawat S, Prachayasittikul V. Metal Complexes of Uracil Derivatives with Cytotoxicity and Superoxide Scavenging Activity. Lett. Drug Des. Discov. 2012; 9: 282-287. Abstract
  12. Worawittayanon P, Ruadreo J, Disadee W, Sahakitpichan P, Sitthimonchai S, Thasana N, Ruchirawat S, Kanchanapoom T. Iridoid and Flavone Glycosides from Asystasia gangetica subsp. micrantha and Asystasia salicifolia and Their Antioxidant Activities. Biochem. Syst. Ecol. 2012; 40: 38-42. Abstract
  13. Disadee W, Mahidol C, Sahakitpichan P, Sitthimonchai S, Ruchirawat S, Kanchanapoom T. Unprecedented Furan-2-carbonyl C-Glycosides and Phenolic Diglycosides from Scleropyrum pentandrum. Phytochemistry 2012; 74: 115-122. Abstract
  14. Prachayasittikul S, Worachartcheewan A, Yainoy S, Lomchoey N, Kittiphatcharin P, Ruchirawat S, Prachayasittikul V. Antioxidant and Antimicrobial Activities of Saraca thaipingensis Cantley ex Prain. Asian Pac. J. Trop. Biomed. 2012; 2: S796-S799. Abstract
  15. Adachi M, Higuchi K, Thasana N, Yamada H, Nishikawa T. Stereocontrolled Synthesis of an Indole Moiety of Sespendole and Stereochemical Assignment of the Side Chain. Org. Lett. 2012, 14, 114-117. Abstract
  16. Doungsoongnuen S, Worachartcheewan A, Pingaew R, Suksrichavalit T, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Investigation on Biological Activities of Anthranilic Acid Sulfonamide Analogs. EXCLI J. 2011; 10: 155-161. Abstract
  17. Sripha K, Zlotos DP, Holzgrabe U, Ruchirawat S. A New Synthetic Approach to Pentacyclic Ring, 6,7,14,15-Tetrahydro[1,5]Diazocino[1,2-a:6,5-a']-8-Dihydrodiindole. Heterocycles 2011; 83: 2627-2633. Abstract
  18. Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. 3-Hydroxydihydrobenzofuran Glucosides from Gnaphalium polycaulon. Chem. Pharm. Bull. 2011; 59: 1160-1162. Abstract
  19. Hutacharoen P, Ruchirawat S, Boonyarattanakalin S. Biological Activities of Synthetic Oligosaccharides and Glycolipids from Mycobacteria. J. Carbohydr. Chem. 2011; 30: 415-437. Abstract
  20. Treeratanapiboon L, Worachartcheewan A, Suksrichavalit T, Kiatfuengfoo R, Prachayasittikul S, Ruchirawat S, Prachayasittikul V. Bioactive 4-Hydroxycinnamide and Bioactivities of Polyalthia cerasoides. EXCLI J. 2011; 10: 16-22. Abstract
  21. Pailee P, Prachyawarakorn V, Mahidol C, Ruchirawat S, Kittakoop P. Protoberberine Alkaloids and Cancer Chemopreventive Properties of Compounds from Alangium salviifolium. Eur. J. Org. Chem. 2011, (20-21): 3809-3814. Abstract
  22. Bunrit A, Ruchirawat S, Thongsornkleeb C. A Simple Microwave-assisted Preparation of 2-Bromo-1-alkenes from 1-Alkynes using the LiBr-TMSCl-TEAB Reagent System. Tetrahedron Lett. 2011; 52: 3124-3127. Abstract
  23. Disadee W, Mahidol C, Sahakitpichan P, Sitthimonchai S, Ruchirawat S, Kanchanapoom T. Flavonol 3-O-Robinobiosides and 3-O-(2″-O-α-Rhamnopyranosyl)-robinobiosides from Sesuvium portulacastrum. Tetrahedron 2011; 67: 4221-4226. Abstract
  24. Sahakitpichan P, Mahidol C, Disadee W, Ruchirawat S, Kanchanapoom T. Unusual Glycosides of Pyrrole Alkaloid and 4′-Hydroxyphenylethanamide from Leaves of Moringa oleifera. Phytochemistry 2011; 72: 791-795. Abstract
  25. Panseeta P, Lomchoey K, Prabpai S, Kongsaeree P, Suksamrarn A, Ruchirawat S, Suksamrarn S. Antiplasmodial and Antimycobacterial Cyclopeptide Alkaloids from the Root of Ziziphus mauritiana. Phytochemistry 2011; 72: 909-915. Abstract
  26. Kanintronkul Y, Worayuthakarn R, Thasana N, Winayanuwattikun P, Pattanapanyasat K, Surarit R, Ruchirawat S, Svasti J. Overcoming Multidrug Resistance in Human Lung Cancer with Novel Benzo[a]quinolizin-4-ones. Anticancer Res. 2011; 31: 921-927. Abstract
  27. Prachayasittikul S, Worachartcheewan A, Nantasenamat C, Chinworrungsee M, Sornsongkhram N, Ruchirawat S, Prachayasittikul V. Synthesis and Structure-activity Relationship of 2-Thiopyrimidine-4-one Analogs as Antimicrobial and Anticancer Agents. Eur. J. Med. Chem. 2011; 46: 738-742. Abstract
  28. Thipnate P, Chittchang M, Thasana N, Saparpakorn P, Ploypradith P, Hannongbua S. Exploring the Molecular Basis for Selective Cytotoxicity of Lamellarins against Human Hormone-dependent T47D and Hormone-independent MDA-MB-231 Breast Cancer Cells. Monatsh. Chem. 2011; 142: 97-109. Abstract
  29. Pungkham H, Swatdipakdi N, Theerasilp M, Chittchang M, Karnkla S, Ploypradith P, Nasongkla N. PEG-b-PCL and PEG-b-PLA Polymeric Micelles as Nanocarriers for Lamellarin N Delivery. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2011, 3245-3248. Abstract
  30. Prachayasittikul S, Pingaew R, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. A New Sulfoxide Analog of 1,2,3,6-Tetrahydrophenylpyridine and Antimicrobial Activity. EXCLI J. 2010; 9: 102-107. Abstract
  31. Noiarsa P, Ruchirawat S, Kanchanapoom T. Acanmontanoside, a New Phenylethanoid Diglycoside from Acanthus montanus. Molecules 2010; 15: 8967-8972. Abstract
  32. Sahakitpichan P, Disadee W, Ruchirawat S, Kanchanapoom T. L-(-)-(N-trans-Cinnamoyl)-arginine, an Acylamino Acid from Glinus oppositifolius (L.) Aug. DC. Molecules 2010; 15: 6186-6192. Abstract
  33. Prachayasittikul S, Wongsawatkul O, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Vasorelaxation and Superoxide Scavenging Activities of Orotic Acid. Int. J. Pharmacol. 2010; 6: 413-418. Abstract
  34. Prachayasittikul S, Wongsawatkul O, Suksrichavalit T, Ruchirawat S, Prachayasittikul V. Bioactivity Evaluation of Eclipta prostrate Linn: a Potential Vasorelaxant. Eur. J. Sci. Res. 2010; 44: 167-176. Abstract
  35. Lirdprapamongkol K, Sakurai H, Suzuki S, Koizumi K, Prangsaengtong O, Viriyaroj A, Ruchirawat S, Svasti J, Saiki I. Vanillin Enhances TRAIL-induced Apoptosis in Cancer Cells through Inhibition of NF-κB Activation. In Vivo 2010; 24: 501-506. Abstract
  36. Thasana N, Prapagdee B, Rangkadilok N, Sallabhan R, Aye SL, Ruchirawat S, Loprasert S. Bacillus subtilis SSE4 produces subtulene A, A New Lipopeptide Antibiotic Possessing an Unusual C15 Unsaturated β-Amino Acid. FEBS Lett. 2010; 584: 3209-3214. Abstract
  37. Yongyat C, Ruchirawat S, Boonyarattanakalin S. Polymerization of Mannosyl Tricyclic Orthoesters for the Synthesis of α(1-6) Mannopyranan-the Backbone of Lipomannan. Bioorg. Med. Chem. 2010; 18: 3726-3734. Abstract
  38. Chanthateyanonth R, Ruchirawat S, Srisitthiratkul C. Preparation of New Water-Soluble Chitosan Containing Hyperbranched-vinylsulfonic Acid Sodium Salt and Their Antimicrobial Activities and Chelation with Metals. J. Appl. Polym. Sci. 2010; 116: 2074-2082. Abstract
  39. Prachayasittikul S, Saraban P, Cherdtrakulkiat R, Ruchirawat S, Prachayasittikul V. New Bioactive Triterpenoids and Antimalarial Activity of Diospyros rubra Lec. EXCLI J. 2010; 9: 1-10. Abstract
  40. Pingaew R, Prachayasittikul S, Ruchirawat S. Synthesis, Cytotoxic and Antimalarial Activities of Benzoyl Thiosemicarbazone Analogs of Isoquinoline and Related Compounds. Molecules 2010; 15: 988-996. Abstract
  41. Prachayasittikul S, Wongsawatkul O, Worachartcheewan A, Nantasenamat C, Ruchirawat S, Prachayasittikul V. Elucidating the Structure-activity Relationships of the Vasorelaxation and Antioxidation Properties of Thionicotinic Acid Derivatives. Molecules 2010; 15: 198-214. Abstract
  42. van Duursen MBM, Nijmeijer SM, Ruchirawat S, van den Berg M. Chemopreventive Actions by Enterolactone and 13 VIOXX®-related Lactone Derivatives in H295R Human Adrenocortical Carcinoma Cells. Toxicol. Lett. 2010; 192: 271-277. Abstract
  43. Prachayasittikul S, Limnusont P, Pingaew R, Ruchirawat S, Prachayasittikul V. β-(1-Adamantylthio)pyridine Analogs as Antimicrobials and Antimalarials. EXCLI J. 2009; 8: 35-40. Abstract
  44. Prachayasittikul S, Treeratanapiboon L, Ruchirawat S, Prachayasittikul V. Novel Activities of 1-Adamantylthiopyridines as Antibacterials, Antimalarials and Anticancers. EXCLI J. 2009; 8: 121-129. Abstract
  45. Prachayasittikul S, Buttrawong K, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Isolation of Bioactive Metabolites from Root Extracts of Polyalthia debilis. Eur. J. Sci. Res. 2009; 38: 596-603. Abstract
  46. Prachayasittikul S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V. Activities of Thiotetrahydropyridines as Antioxidant and Antimicrobial Agents. EXCLI J. 2009; 8: 107-114. Abstract
  47. Prachayasittikul S, Manam P, Chinworrungsee M, Isarankura-Na-ayudhya C, Ruchirawat S, Prachayasittikul V. Bioactive Azafluorenone Alkaloids from Polyalthia debilis (Pierre) Finet & Gagnep. Molecules 2009; 14: 4414-4424. Abstract
  48. Prachayasittikul S, Sornsongkhram N, Pingaew R, Techatanachai S, Ruchirawat S, Prachayasittikul V. Synthesis and Novel Bioactivities of Substituted 6-Propylthiouracils. Eur. J. Sci. Res. 2009; 36: 236-245. Abstract
  49. Prachayasittikul S, Sornsongkhram N, Pingaew R, Worachartcheewan A, Ruchirawat S, Prachayasittikul V. Synthesis of N-Substituted 5-Iodouracils as Antimicrobial and Anticancer Agents. Molecules 2009; 14: 2768-2779. Abstract
  50. Siripong P, Hahnvajanawong C, Yahuafai J, Piyaviriyakul S, Kanokmedhakul K, Kongkathip N, Ruchirawat S, Oku N. Induction of Apoptosis by Rhinacanthone Isolated from Rhinacanthus nasutus Roots in Human Cervical Carcinoma Cells. Biol. Pharm. Bull. 2009; 32: 1251-1260. Abstract
  51. Sangjun S, de Jong E, Nijmeijer S, Mutarapat T, Ruchirawat S, van den Berg M, van Duursen MB. Induction of Cell Cycle Arrest in Human MCF-7 Breast Cancer Cells by cis-Stilbene Derivatives Related to VIOXX®. Toxicol. Lett. 2009; 186: 115-122. Abstract
  52. Khorana N, Markmee S, Ingkaninan K, Ruchirawat S, Kitbunnadaj R, Pullagurla MR. Evaluation of a New Lead for Acetylcholinesterase Inhibition. Med. Chem. Res. 2009; 18: 231-241. Abstract
  53. Prachayasittikul S, Suphapong S, Worachartcheewan A, Lawung R, Ruchirawat S, Prachayasittikul V. Bioactive Metabolites from Spilanthes acmella Murr. Molecules 2009; 14: 850-867. Abstract
  54. Prompiboon P, Bhumiratana A, Ruchirawat S, Boucias DG, Wiwat C. Isolation of Ergosterol Peroxide from Nomuraea rileyi Infected Larvae of Tobacco Cutworm. World J. Microbiol. Biotechnol. 2008; 24: 2909-2917. Abstract
  55. Wongsawatkul O, Prachayasittikul S, Isarankura-Na-Ayudhya C, Satayavivad J, Ruchirawat S, Prachayasittikul V. Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr. Int. J. Mol. Sci. 2008; 9: 2724-2744. Abstract
  56. Sanderson T, Renaud M, Scholten D, Nijmeijer S, van den Berg M, Cowell S, Guns E, Nelson C, Mutarapat T, Ruchirawat S. Effects of Lactone Derivatives on Aromatase (CYP19) Activity in H295R Human Adrenocortical and (Anti)androgenicity in Transfected LNCaP Human Prostate Cancer Cells. Eur. J. Pharmacol. 2008; 593: 92-98. Abstract
  57. van Meeuwen JA, Nijmeijer S, Mutarapat T, Ruchirawat S, de Jong PC, Piersma AH, van den Berg M. Aromatase Inhibition by Synthetic Lactones and Flavonoids in Human Placental Microsomes and Breast Fibroblasts - a Comparative Study. Toxicol. Appl. Pharmacol. 2008; 228: 269-276. Abstract
  58. Prachayasittikul S, Buraparuangsang P, Worachartcheewan A, Isarankura-Na-Ayudhya C, Ruchirawat S, Prachayasittikul V. Antimicrobial and Antioxidative Activities of Bioactive Constituents from Hydnophytum formicarum Jack. Molecules 2008; 13: 904-921. Abstract
  59. Noiarsa P, Ruchirawat S, Otsuka H, Kanchanapoom T. Chemical Constituents from Oldenlandia corymbosa L. of Thai Origin. J. Nat. Med. 2008; 62: 249-250. Abstract
  60. Kaewkrud W, Otsuka H, Ruchirawat S, Kanchanapoom T. Megastigmane and Flavone Glycosides from Strophioblachia fimbricalyx Boerl. J. Nat. Med. 2008; 62: 124-125. Abstract
  61. Baunbæk D, Trinkler N, Ferandin Y, Lozach O, Ploypradith P, Ruchirawat S, Ishibashi F, Iwao M, Meijer L. Anticancer Alkaloid Lamellarins Inhibit Protein Kinases. Mar. Drugs 2008; 6: 514-527. Abstract